Fig. 5

p-curve analysis plots of log-HRs (A) and log-MSRs (B) in preclinical experiments of ICB. For each treatment, a p-curve analysis was conducted to determine the number of missing studies due to potential publication bias. Figure shows a subset of treatments from the total 53 of preclinical therapies: anti-CTLA-4, anti-PD-1, anti-PD-L1, anti-CTLA-4 + anti-PD-1, anti-CTLA-4 + anti-PD-L1, anti-CTLA-4 + Chemotherapy, anti-PD-1 + Chemotherapy, and anti-PD-L1 + Chemotherapy