Fig. 4
From: Efficacy of derinat as a treatment for murine and androgenetic alopecia (AGA) patients
AGA features TRPCs-activated Ca2+ signals, ROS accumulation and inflammation. A Gene Expression Omnibus (GEO) database analysis of TRPCs, oxidative stress-related genes, and inflammation-related genes in the scalp of healthy donor and AGA patients. Comparison of TRPCs, oxidative stress-related genes, and inflammation-related genes in (B) the bulge, bulb and (C) DP (papilla cells) between non-balding area and balding area of AGA patients (mean ± SD; *, p < 0.05; **, p < 0.01; ***, p < 0.001). D TRPCs-activated Ca2+ signals govern the inflammation and oxidative stress KEGG pathways in AGA