Table 2 Pharmacokinetics of iMN013 released from iMN041 formulated in FS-14 or FS-19. Where: Cmax is the maximum concentration, Tmax is the time associated with Cmax, T1/2 is the half-life, MRT is the mean residence time and AUC is the area under the curve
Formulation | Cmax (ng/mL) | Tmax (h) | T1/2 (h) | MRT0-last (h) | AUC0-last (h) |
|---|---|---|---|---|---|
FS-14 | 1630 | 0.5 | 1.02 | 1.83 | 3624 |
FS-19 | 1770 | 0.5 | 1.40 | 2.27 | 4815 |