Fig. 6

Summary image to illustrate main findings of the study. Indicated are the time points before and under consolidation treatment cycles when patient neutrophils were isolated from peripheral blood and functionally tested, as well as direct in vitro treatment of isolated neutrophils. The effect on the different functions, chemotaxis, reactive oxygen burst, NET formation, and ANC (count) are depicted by arrows in relation to healthy donor neutrophils. An upward-oriented arrow represents an increased, a downward-oriented arrow represents a decreased functionality. A dash represents unchanged functionality compared to control. An “X” means that the function is not applicable for the respective condition