Table 1 Peak eosinophil count (PEC) and histopathology scores for esophageal biopsies
Cohort (n = 33) | Pa | ||||
|---|---|---|---|---|---|
nonEoE (n = 11) | aEoE (n = 11) | iEoE (n = 11) | aEoE vs. nonEoE | aEoE vs. iEoE | |
PEC (eos/hpf) | 0 (0–0) | 62 (44–116) | 3 (0–4) | < 0.005 | < 0.005 |
Eosinophilic Inflammation | 0 (0–1) | 2 (2–3) | 1 (0–1) | < 0.005 | < 0.005 |
Basal Zone Hyperplasia | 0 (0–1) | 3 (3–3) | 1 (0–1) | < 0.005 | < 0.005 |
Eosinophilic Abscess | 0 (0–0) | 1 (0–3) | 0 (0–0) | < 0.005 | < 0.005 |
Eosinophil Surface Layering | 0 (0–0) | 1 (0–3) | 0 (0–0) | < 0.005 | < 0.005 |
Dilated Intercellular Spaces | 0 (0–0) | 3 (2–3) | 0 (0–1) | < 0.005 | < 0.005 |
Surface Epithelial Alteration | 0 (0–0) | 0 (0–2) | 0 (0–0) | 0.02 | 0.03 |
Dyskeratotic Epithelial Cells | 0 (0–0) | 0 (0–1) | 0 (0–0) | 0.02 | 0.02 |
Lamina Propria Fibrosis | 0 (0–0) | 2 (2–3) | 0 (0–1) | < 0.005 | < 0.005 |
EoEHSS Grade | 0 (0-0.13) | 1.63 (1.13–2.25) | 0.13 (0.13–0.50) | < 0.005 | < 0.005 |