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Fig. 2 | Translational Medicine Communications

Fig. 2

From: Membrane cholesterol depletion reduces breast tumor cell migration by a mechanism that involves non-canonical Wnt signaling and IL-10 secretion

Fig. 2

Levels of cholesterol and proteins are enhanced in the cultured media following treatment with MbCD in MDA-MB 231 cells. (a and b) The amount of cholesterol and proteins was estimated in the following conditions: growth medium immediately before MbCD treatment (0 h) and at the end of MbCD treatment (2 h), as well as at 5, 8, 12 or 24 h after treatment. Note a high increase in the amount of cholesterol present in the culture medium only after 2 h of MbCD treatment, and an increase in total protein levels only after 12 h of treatment. Each bar represents the mean and standard error of 3 independent experiments. *p < 0.05 and ***p < 0.001; ANOVA versus control group (0 hs)

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