Fig. 8
From: Optimization of CFTR-mRNA transfection in human nasal epithelial cells
Statistical evaluation of the amiloride-sensitive current in dependence of the wtCFTR-mRNA. a Shown is the decreasing trend in ENaC expression in primary HNE cells 24 h after wtCFTR-mRNA transfection using different concentrations 2.4 μg/cm2 (32.85 % ± 3.8; n = 34), 1.2 μg/cm2 (27.92 % ± 5.1; n = 18), 0.6 μg/cm2 (25.03 % ± 5.9; n = 19). There is no statistical significance. b Shown is the increasing trend in ENaC expression in primary HNE cells after 0.6 μg/cm2 wtCFTR-mRNA transfection using different time periods: 24 h (25.03 % ± 5.9; n = 19), 48 h (29.51 % ± 8.1) and 72 h (29.44 % ± 12). No statistical difference was found