| |
Day 2
|
Day 5
|
Day 7
|
Day 28
|
|---|
| |
Control (n = 3)
|
TB4i.p. (n = 5)
|
Control (n = 3)
|
TB4 i.p. (n = 5)
|
Control (n = 3)
|
TB4 i.p. (n = 5)
|
Control (n = 9)
|
TB4 i.p. (n = 10)
|
TB4 i.mc. (n = 10)
|
|---|
|
Body weight at day 0 (g)
|
25.8 ± 0.2
|
25.4 ± 1.9
|
24.2 ± 0.9
|
24.6 ± 2.3
|
25.5 ± 1.3
|
25.5 ± 0.9
|
26.6 ± 1.5
|
27.9 ± 2.3
|
27.0 ± 1.3
|
|
∆ body weight day 0 vs day 28 (g)
|
−1.9 ± 2.3
|
−1.9 ± 1.1
|
−0.5 ± 0.9
|
−0.8 ± 0.7
|
0.4 ± 1.3
|
−2.5 ± 2.4
|
3.2 ± 1.0
|
1.5 ± 1.6*
|
2.1 ± 1.6
|
|
Heart weight (mg)
|
114 ± 2
|
117 ± 3
|
118 ± 13
|
118 ± 7
|
134 ± 16
|
120 ± 11
|
152 ± 16
|
151 ± 26
|
148 ± 20
|
|
Heart to body weight ratio (mg/g)
|
4.8 ± 0.4
|
5.0 ± 0.2
|
5.1 ± 0.5
|
5.0 ± 0.4
|
5.2 ± 0.8
|
5.2 ± 0.3
|
5.1 ± 0.4
|
4.9 ± 0.5
|
5.1 ± 0.6
|
- * = p < 0.05 compared to control, all other p = NS (mean ± SD)
