Table 1 Demographic, clinical, histological and virological characteristics of patients at baseline
Parameter | Patients treated with Peg-IFNα + RBV |
|---|---|
N | 144 |
Mean age (years) | 43.8 ± 7.8 |
Sex (M/F) | 82/62 |
Systolic blood pressure (SBP) mmHg | 132.6 ± 10.8 |
Diastolic Blood Pressure (DBP) mmHG | 81.8 ± 6.7 |
Heart Rate (HR) beats/min | 81.4 ± 6.6 |
HCV exposure time (years) | 5.64 ± 6.8 |
BMI (kg/m2) | 25.8 ± 4.8 |
Route of transmission of HCV (No of patients) | |
Blood transfusion | 86 |
Intravenous drug abuse | 26 |
Occupational | 12 |
Unknown | 20 |
HCV genotype | |
1a | 9 |
1b | 125 |
Blue collars (manual labourers) | 50 |
White collars (non manual/office labourers) | 94 |
Laboratory parameters | |
Plasma glucose (mmol/l) (normal 3.9-6.4) | 5.41 ± 0.96 |
AST (IU/l) (normal 15-50) | 162 ± 38 |
ALT (IU/l) (normal 15-50) | 171 ± 44 |
Viremia (106 IU/ml) | 5.04 ± 3.12 |
CRP (mg/dl) (normal <1.0) | 4.6 ± 0.7 |
HAI (histological activity index) | 10.1 ± 3.6 |