Table 3 Total lymphocytes count (TLC) at start and at end of treatment
TLC at start of treatment [cells/μL] | TLC at end of treatment [cells/μL] | Difference (end – start)[cells/μL] | probability estimatea | |
|---|---|---|---|---|
All patients n = 48 | ||||
Mean value ± SD; range | 902 ± 414; 130–1499 | 1113 ± 466; 220–1135 | 211 ± 442; −1110–1900 | p = 0.0018 |
25% Percentile | 532.5 | 742.5 | 25.0 | |
50% Percentile (Median) | 920.0 | 1135.0 | 115.0 | |
75% Percentile | 1315.0 | 1440.0 | 395.0 | |
Patients with severe lymphopenia (lymphocytes < 1000/μL) n = 25 | ||||
Mean value ± SD; range | 551 ± 212; 130–960 | 919 ± 447; 380–2420 | 368 ± 449; −110–1900 | p = 0.0004 |
25% Percentile | 390.0 | 585.0 | 30.0 | |
50% Percentile (Median) | 540.0 | 820.0 | 240.0 | |
75% Percentile | 705.0 | 1180.0 | 610.0 | |
Patients without moderate lymphopenia (lymphocytes 1000–1500/μL) n = 23 | ||||
Mean value ± SD range | 1283 ± 161; 1000–1499 | 1323 ± 396; 220–1870 | 40 ± 372; −1110–660 | p = 0.6105 |
25% Percentile | 1120.0 | 1150.0 | 20.0 | |
50% Percentile (Median) | 1320.0 | 1400.0 | 100.0 | |
75% Percentile | 1180.0 | 1620.0 | 180.0 | |