Fig. 3
From: Glyceraldehyde-3-phosphate dehydrogenase is overexpressed in colorectal cancer onset
Correlation between GAPDH expression and TNM classifications. a GAPDH expression in relation to the primary tumour extent in all 62 patients and (b) in patients who had not developed distant metastasis. In both cases, GAPDH expression is significantly higher in tumours that have only affected the most external layers of the colonic wall (submucosa and muscularis propria) than in tumours in more invasive stages (invasion into the subserosa, non-peritonealised pericolic or perirectal tissues, other organs and/or perforation of visceral peritoneum). c The presence of metastases in regional lymph nodes is correlated with a significant decrease in primary tumour GAPDH expression. d In the absence of distant metastasis, tumours express significantly higher levels of GAPDH