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Table 1 Demographic, clinical and tumour-related characteristics of patients included in the study (n  =  62)

From: Glyceraldehyde-3-phosphate dehydrogenase is overexpressed in colorectal cancer onset

Age (years)a

 

69.5 ± 11.4

Gender – n° (%)

Male

45 (72.6)

Female

17 (27.4)

Family history of colorectal cancer – n° (%)

 

10 (16.1)

Fulfillment of revised Bethesda guidelines – n° (%)

 

14 (22.6)

Tumour location – n° (%)

Proximal to splenic flexure

19 (30.6)

Distal to splenic flexure

43 (69.4)

TNM tumour stage – n° (%)

I

9 (14.5)

II

21 (33.9)

III

16 (25.8)

IV

16 (25.8)

Tumour size (mm)a

 

43 ± 20

Differentiation degree – n° (%)

Well

6 (9.7)

Moderate

51 (82.2)

Poor

5 (8.1)

Mucinous carcinoma type – n° (%)

 

10 (16.1)

Mismatch repair deficiency – n° (%)b

 

4 (6.5)

Synchronous colorectal cancer – n° (%)

 

5 (8.1)

Synchronous colorectal adenoma – n° (%)

 

23 (37.1)

Surgical treatment – n° (%)

Right colectomy

16 (25.8)

Left colectomy

6 (9.7)

Sigmoidectomy

22 (35.5)

Anterior resection

9 (14.5)

Total colectomy

6 (9.7)

Abdominoperineal resection (Miles)

3 (4.8)

Chemotherapy – n° (%)c

 

35 (56.5)

Length of follow-up (months)d

 

49 (40–53)

  1. aExpressed as mean ± standard deviation
  2. bAll four cases correspond to loss of MLH1 protein expression
  3. cAll chemotherapeutic regimens included 5-fluorouracil, five of them in combination with oxaliplatin and two in combination with irinotecan
  4. dExpressed as median (range)