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Table 14 Chromosome 12 (−) strand chromatin consensus sequence recognition (CSR) and somatic hypermutation (SHM) enzyme gene, AICDA, and chromosome 22 (+) strand CSR and SHM gene, APOBEC3A through APOBEC3H, sequential esebssiwaagoTQs to final 2-digit (and 3-Q digit) esebssiwaagoTQ

From: B-cell differentiation is pressuromodulated as determined by pressuromodulation mapping: Part I, cell differentiation

Gene Symbol

No. of Episodes [Initial no. of SEBs (final no. of SEBs)]a-e

\( \underset{0}{\overset{1}{\int }} \)

\( \underset{0}{\overset{2}{\int }} \)

\( \underset{0}{\overset{3}{\int }} \)

\( \underset{0}{\overset{4}{\int }} \)

\( \underset{0}{\overset{5}{\int }} \)

\( \underset{0}{\overset{6}{\int }} \)

\( \underset{0}{\overset{7}{\int }} \)

\( \underset{0}{\overset{8}{\int }} \)

\( \underset{0}{\overset{9}{\int }} \)

\( \underset{0}{\overset{10}{\int }} \)

\( \underset{0}{\overset{11}{\int }} \)

AICDA

3 M (7) ACM × 2

0.50

0.38

0.33

0.27

0.27

0.27

0.27 (0.266)

    

APOBEC3A/APOBEC3B

2 M (5) stIMfA NCA

0.60

0.19

0.23

0.23

0.22 (0.216)

      

APOBEC3C/APOBEC3D/APOBEC3F/

APOBEC3G

2 A (5) NCA

0.08

0.20

0.23

0.18

0.17 (0.173)

      

APOBEC3H

3 M [7(+ 4): 11] ACM ×2 NCA

0.71

0.37

0.32

0.08

0.07

0.08

0.09

0.11

0.11

0.10

0.10 (0.102)

  1. a1st episode beginning with an anisotropic sub-episode block (SEB), A, or beginning with a mesotropic SEB, M; bnon-contributory anisotropic sub-episode block (NCA); cnon-contributory single or multiple stabilizing isotropy points or reverse stabilizing isotropy point(s), NCstI; danisotropy converted-to-mesotropy, ACM; and eindirect reverse stIsotropy and/or stIsotropy for anisotropy, stMfA, or for mesotropy, stMfM