From: B-cell antibody class switchings are pressuromodulated events: Part II, gene recombination
Germline Genea | Germline gene locusa | Total no. of transcribed bases at gene locus or n/a (episode category)b | Initial no. of sub-episode blocks (converted final no. of sub-episode blocks, or n/a) | Germline gen e 2-digit (3-digit) esebssiwaagoTQ | Predicted gene recombination wrt allele 1 (IGHM), allele 2 (IGHD), both, or neither |
---|---|---|---|---|---|
IGHA2 | IGHA2 | 1508 (3) | 7 (n/a) | 0.10 (0.099) | Allele 1; Allele 2 after initial allelic exclusion |
IGHE | ENSG00000227468/IGHE/ENSG00000254140 | 7667 (3) | 7 (n/a) | 0.11 (0.111) | Allele 1; Allele 2 after initial allelic exclusion |
IGHG4 & IGHG2 | lnc-JAG2–1/IGHG4 /IGHG2/ ENSG00000253364 | 30,527 (2) | 7 (5) | 0.16 (0.163) | Allele 1; Allele 2 after initial allelic exclusion |
IGHA1 | IGHA1 | 1548 (3) | 7 (n/a) | 0.13 (0.131) | Allele 1; Allele 2 after initial allelic exclusion |
IGHG1 | IGHG1 | 6729 (3) | 7 (n/a) | 0.12 (0.120) | Allele 1; Allele 2 after initial allelic exclusion |
IGHG3 | GC14M105753/IGHG3 | 20,987 (2) | 7 (5) | 0.08 (0.075) | Allele 1; Allele 2 after initial allelic exclusion |
IGHD | IGHD | 8914 (3) | 7 (n/a) | 0.09 (0.092) | Allele 2 HR except in initial allelic exclusion |
IGHM | IGHM | 6729 (3) | 7 (n/a) | 0.09 (0.088) | Allele 1; Allele 2 after initial allelic exclusion |
MIR4539 | MIR4539 | 60 (3) | 7 (n/a) | 0.08 (0.076) | iCSR for Allele 1 (IGHM); Allele 2 (IGHD) delayed iCSR after initial allelic exclusion |
MIR4507 & MIR4538 | MIR4507/ MIR4538 | 119 (3) | 7 (n/a) | 0.08 (0.081) | iCSR for Allele 1 (IGHM); Allele 2 (IGHD) delayed iCSR after initial allelic exclusion |
MIR4537 | MIR4537 | 70 (3) | 7 (n/a) | 0.06 (0.064) | iCSR for Allele 1 (IGHM); Allele 2 (IGHD) delayed iCSR after initial allelic exclusion |