Table 2 Chromosome 14 (−) strand chromatin Ig heavy chain locus joining gene esebssiwaagoTQs for germline genes in native 5′- > 3′ chronology before gene rearrangement
From: B-cell antibody class switchings are pressuromodulated events: Part II, gene recombination
Germline Genea | Germline gene locusa | Total no. of transcribed bases at gene locus or n/a (episode category)b | Initial no. of sub-episode blocks (converted final no. of sub-episode blocks, or n/a) | Germline gen e 2-digit (3-digit) esebssiwaagoTQ | Predicted gene recombination wrt allele 1 (IGHM), allele 2 (IGHD), both, or neither |
|---|---|---|---|---|---|
IGHJ6 | IGHJ6 | 65 (3) | 7 (n/a) | 0.10 (0.097) | Allele 1 (D → J step 2 of 2 for IGHM) |
IGHJ5 | IGHJ5 | 53 (3) | 7 (n/a) | 0.24 (0.235) | Allele 1 (D → J step 1 of 1 & step 1 of 2 for IGHM) |
IGHJ4 | IGHJ4 | 50 (3) | 7 (n/a) | 0.11 (0.110) | Allele 2 (D → J step 2 of 2 for IGHD) |
IGHJ3 | IGHJ3 | 52 (3) | 7 (n/a) | 0.11 (0.112) | Allele 2 (D → J step 1 of 1 for IGHD) |
IGHJ2 | IGHJ2 | 55 (3) | 7 (n/a) | 0.11 (0.114) | Allele 2 (D → J step 1 of 1 & step 1 of 2 for IGHD) |
IGHJ1 | IGHJ1 | 54 (3) | 7 (n/a) | 0.12 (0.116) | Allele 2 (D → J step 1 of 1 for IGHD) |