Fig. 1

Haploview graph of SHBG SNPs analyzed. The positions of the seven SNPs used (Build 37.3) are indicated along with the basic gene structure, and displayed above the Haploview output. The relative LD between specific pair of SHBG SNPs is indicated by the color scheme, which represents the LD relationships. This is based on D’ values (normalized linkage disequilibrium measure or D) multiplied by 100; D’ is calculated as D divided by the theoretical maximum for the observed allele frequencies. Values approaching zero indicate absence of LD, and those approaching 100 indicate complete LD. The square colored red represent varying degrees of LD < 1 and LOD (logarithm of odds) > 2 scores; darker shades indicating stronger LD