Common genetic variants in the sex hormone-binding globulin (SHBG) gene in idiopathic recurrent pregnancy loss: a case control study

Table 1 Demographics & Clinical Characteristics of Cases and Controls

	Cases^a	Controls^a	P ^b
Age at inclusion in study ^c	31.6 ± 5.4	31.6 ± 4.9	0.94
Body-mass index (kg/m²) ^c	26.3 ± 5.4	25.2 ± 4.3	0.004
Obesity [n (%)] ^d	58 (19.6)	37 (12.1)	0.02
Smokers [n (%)] ^d	30 (10.1)	32 (10.8)	0.69
Systolic blood pressure (mmHg) ^c	114.2 ± 11.9	120.2 ± 17.0	< 0.001
Diastolic blood pressure (mmHg) ^c	72.0 ± 8.4	75.8 ± 9.1	< 0.001
Glucose (mmol/L) ^c	5.1 ± 0.9	5.2 ± 0.7	0.55
Menarche (years)^c	12.2 ± 1.1	12.8 ± 1.0	< 0.001
Number of pregnancies ^c	4.2 ± 1.5	4.0 ± 1.1	0.11
Number of Children ^c	0.8 ± 1.1	4.0 ± 1.1	< 0.001
Miscarriages ^c	3.6 ± 1.0	0.0 ± 0.1	< 0.001
Serum IL-10 (pg/ml) ^c	5.3 ± 1.8	6.1 ± 1.2	0.002

^aA total of 308 RPL cases and 310 control women were included
^bStudent’s t-test (continuous variables), Pearson’s χ² test (categorical variables)
^cMean ± SD
^dPercent of total within each group/subgroup

ISSN: 2396-832X