Common genetic variants in the sex hormone-binding globulin (SHBG) gene in idiopathic recurrent pregnancy loss: a case control study

Table 2 SHBG SNPs analyzed in RPL cases and control women

#	SNP	Position	HWE P	Alleles	Cases ^a	Controls ^a	χ²	P	aOR ^b (95% CI)	Power
1	rs9898876	7,623,644	0.154	G:T	0.121	0.089	2.453	0.117		90
2	rs13894	7,626,584	0.149	C:T	0.345	0.370	0.751	0.386		63
3	rs858521	7,626,829	0.461	C:G	0.536	0.494	1.832	0.176		100
4	rs1799941	7,630,105	0.686	G:A	0.175	0.206	1.603	0.206		83
5	rs6257	7,630,399	0.084	T:C	0.163	0.249	10.82	0.001	0.59 (0.43–0.81)	100
6	rs6259	7,633,209	0.050	G:A	0.041	0.039	0.011	0.917		89
7	rs727428	7,634,474	0.783	G:A	0.411	0.433	0.262	0.609		42

^aMAF frequency
^baOR = adjusted OR; variables that were controlled for were BMI, menarche, systolic and diastolic blood pressure

ISSN: 2396-832X