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Table 5 Haplotype frequencies across 7 SHBG SNPs analyzed a

From: Common genetic variants in the sex hormone-binding globulin (SHBG) gene in idiopathic recurrent pregnancy loss: a case control study

Haplotypeb

Frequency

Case:Control frequencies

χ2

P

aOR (95% CI)

C C G T G A

0.138

0.165; 0.108

7.405

6.5 × 10−3

1.66 (1.16–2.38)

C G G T G G

0.128

0.132; 0.124

0.163

0.687

 

C C A T G G

0.115

0.106; 0.125

1.001

0.317

 

T G G T G G

0.087

0.092; 0.081

0.420

0.517

 

C G G C G G

0.069

0.061; 0.078

1.158

0.282

 

T C G T G A

0.066

0.064; 0.067

0.030

0.863

 

C G G C G A

0.060

0.047; 0.074

3.422

0.064

 

T G G C G A

0.055

0.045; 0.067

2.411

0.121

 

C C G T G G

0.054

0.062; 0.045

1.626

0.202

 

T C A T G G

0.052

0.052; 0.052

0.001

0.986

 

T C G T G G

0.047

0.044; 0.051

0.329

0.567

 

C G G T G A

0.047

0.048; 0.045

0.055

0.814

 
  1. aSHBG haplotypes: rs13894- rs858521- rs1799941- rs6257- rs6259- rs727428
  2. bUnderlined indicates minor allele