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Table 1 Statistical results of surgical impression/ advance optical imaging vs histologic gold standard

From: Endogenous fluorescence of hemosiderin in endometriosis to improve clinical detection

 

PPV

NPV

SENS.

SPEC.

Surgical Impression (27 subjects)

68

96

98

53

OCT-TPM Combined (18 subjects with advanced imaging)

100

93

93

100

TPM for Hemosiderin (113 optical imaging sets)

100

100

100

100

OCT for Glands (113 optical imaging sets)

 

96

82

 
  1. PPV is positive predictive value, NPV is negative predictive value, SENS is sensitivity, SPEC is specificity
  2. Surgical Impression is based on the surgical diagnosis of all samples taken from 27 subjects against histological diagnosis. OCT-TPM combined is the optical markers from both imaging type predication of endometriosis against histological diagnosis. OCT-TPM was only available in 18 of 27 patients with endometriosis. One hundred thirteen optical imaging sets were available from these 18 patients for OCT-TPM. OCT for glands lacks a PPV and specificity due to lack of a true false positive. TPM for hemosiderin and OCT for glands is specifically the identification of the marker in the imaging data against histologic confirmation of the marker