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Table 4 Evaluation of BALF and BALC form study participants

From: Performance and immune characteristics of bronchoalveolar lavage by research bronchoscopy in pulmonary tuberculosis and other lung diseases in the Western Cape, South Africa

 

TB (n = 17)

Healthy (n = 11)

OLD (n = 19)

Saline and BALF

 Med saline volume (ml) in (min-max)

190 (60–300)

170 (120–240)

180 (120–300)

 Med BALF volume (ml) out (min-max)

65 (40–125)

90 (45–135)

90 (37–155)

 Fluid volume ratio out/in (min-max)

0.31 (0.17–0.67)

0.54 (0.20–0.67)

0.49 (0.12–0.86)

Cellular (based on differential cell counts)

 Cell pellet colour (Black/Clear)

12/5

7/4

8/11

 Total med BALC count (×106) (min-max)

38.00 (26.40–54.00)a

21.15 (11.25–81.60)

16.20 (6.50–43.40)a

 Med BALC concentration (×106/ml) (min-max)

0.68 (0.10–1.39)

0.44 (0.14–1.31)

0.49 (0.12–0.86)

 Med % Monocytes/Macrophages (min-max)

81.00 (0.00–88.00)b,c

89.00 (70.00–98.00)b

80.50 (5.00–98.00)c

 Med % Neutrophils (min-max)

10.00 (2.00–100.00)d,e

0.00 (0.00–4.00)d

9.00 (0.00–21.00)e

 Med % Lymphocytes (min-max)

9.00 (0.00–13.00)f

11.00 (2.00–30.00)f

7.00 (0.00–30.00)

  1. a-f Illustrates statistical differences of data readouts between cohorts. Significance determined at P < 0.05 using ANCOVA with Fisher’s LSD as post hoc for all pairwise comparisons. Statistical analysis factors in co-variant data of gender and age differences between cohorts
  2. TB tuberculosis, OLD other lung disease, med median, min minimum, max maximum, ml millilitre, % percentage