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Table 1 The S-plot proteins differing between samples from patients with right-sided stage II and III CRC

From: Differences and overlap in plasma protein expression during colorectal cancer progression

Accession Peptide count Unique peptides Confidence score Mann-Whitney U test p-value Fold change (right colon stage II/right colon III) Protein name Gene name p [1] p (corr) [1]
O95568 8 3 32,4 4,37E−05 1,6 Histidine protein methyltransferase 1 homolog METTL18 −0,02 −0,86
P09429 5 2 29,5 1,43E− 04 1,8 High mobility group protein B1 HMGB1 −0,03 − 0,82
P68032;P62736;P68133;P63267 21 3 208,1 1,66E−03 1,8 Actin_ alpha cardiac muscle 1 ACTC1 −0,04 −0,82
P01344 7 4 27,5 1,66E−03 1,4 Insulin-like growth factor II IGF2 −0,02 −0,77
Q96KN2 19 15 128,0 3,08E−03 1,4 Beta-Ala-His dipeptidase CNDP1 −0,06 −0,76
P04083 17 8 99,3 1,95E−03 1,4 Annexin A1 ANXA1 −0,06 −0,71
Q9Y4B5 4 2 19,1 8,64E−04 1,9 Microtubule cr s-linking factor 1 MTCL1 −0,01 −0,69
H7BZ55 9 6 52,9 8,35E−03 1,4 Putative ciliary rootlet coiled-coil protein 2 CROCC2 −0,05 −0,68
Q562R1 12 4 95,6 2,28E−02 1,2 Beta-actin-like protein 2 ACTBL2 −0,02 −0,66
P00740 13 10 71,8 6,14E−04 1,4 Coagulation factor IX F9 −0,03 −0,65
Q6UB98 6 2 36,6 4,79E−03 1,5 Ankyrin repeat domain-containing protein 12 ANKRD12 −0,06 −0,65
H3BMM5 3 2 13,7 1,20E−03 1,4 Uncharacterized protein   −0,02 −0,65
P02775 9 7 66,0 8,00E−05 1,5 Platelet basic protein PPBP −0,04 −0,63
Q14520 24 18 158,5 1,09E−02 1,4 Hyaluronan-binding protein 2 HABP2 -0,04 -0,63
P23508 5 3 27,9 1,09E-02 1,2 Colorectal mutant cancer protein MCC -0,03 -0,63
A5A3E0;Q6S8J3;P0CG39;
Q9BYX7;E7EQ34;O14653
52 14 289,7 1,73E-04 1,4 POTE ankyrin domain family member F POTEF -0,03 -0,62
Q15166 6 2 62,1 1,24E-02 2,9 Serum paraoxonase/lactonase 3 PON3 -0,05 -0,61
O75882 16 12 98,9 4,92E-02 1,2 Attractin ATRN -0,03 -0,60
P35858;Q2M5E4 34 28 275,0 2,03E-02 1,4 Insulin-like growth factor-binding protein complex acid labile subunit IGFALS -0,08 -0,60
P43251 11 7 75,6 1,24E-02 1,5 Biotinidase BTD -0,03 -0,60
Q9Y6X9 5 3 27,1 6,14E-04 −5,7 MORC family CW-type zinc finger protein 2 MORC2 0,02 0,62
  1. These proteins passed the criteria for OPLS-DA modeling and also had a Mann-Whitney U test p-value of less than 0.05. Accession, peptide count, unique peptides, confidence score, p-value, fold change, protein name, gene name, covariance (p [1]), and correlation (p (corr) [1]) are given in the table