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Table 2 The Venn diagram proteins whose levels differed during CRC progression in all locations

From: Differences and overlap in plasma protein expression during colorectal cancer progression

Proteins whose plasma levels differed between samples from patients with stage II and III cancer in all locations

 

Accession

Peptide count

Unique peptides

Confidence score

Protein name

Gene name

Notes

Q15166

6

2

62,1

Serum paraoxonase/lactonase 3

PON3

*

P02766

22

19

214,4

Transthyretin

TTR

 

P02775

9

7

66,0

Platelet basic protein

PPBP

*

O95568

8

3

32,4

Histidine protein methyltransferase 1 homolog

METTL18

 

Q12805

9

8

51,7

EGF-containing fibulin-like extracellular matrix protein 1

EFEMP1

 

Q8TE85

6

3

28,7

Grainyhead-like protein 3 homolog

GRHL3

 

P05455

5

3

28,9

Lupus La protein

SSB

*

A6NMZ7;P51570;Q13158;Q6NT55

5

2

24,3

Collagen alpha-6(VI) chain

COL6A6

 

P09871

54

47

387,7

Complement C1s subcomponent

C1S

 

O75882

16

12

98,9

Attractin

ATRN

 

P23508

5

3

27,9

Colorectal mutant cancer protein

MCC

*

P02790;P51687;Q00973;Q04917;Q5T013;Q9NXR7; Q9NZ08;Q9Y2H2;Q9Y2K5;V9GYY9

182

150

1011,0

Hemopexin

HPX

 

P07357

35

34

217,4

Complement component C8 alpha chain

C8A

 
  1. These 13 proteins are those whose changes in levels were common to CRC progression regardless of tumor location. Accession, peptide count, unique peptides, confidence score, protein name, and gene name are given in the table. The proteins with higher levels in samples from patients with left-sided stage III than stage II CRC are marked with a *. All other proteins had higher levels in patients with stage II cancer