Fig. 1

Angulation of intergene base arc distance tropy in reference to the z, x-axis horizontal plane for amorphous heterochromatin loop segment genes. Amorphous heterochromatin strand loop micro-structural segmentation is a series of intergene base distance-separated alternating anisotropic (a) and mesotropic genes (m) in the form of one or two in-tandem anisotropic or mesotropic genes of the same at angulation (Θ_A, Θ_M) in the z, y-vertical axis plane. The prelamin-A/C gene (P_eff, 0.184)-containing amorphous form heterochromatin strand loop segment for example is arranged as LMNA (Θ_A = 67.8⁰)-SEMA4A (Θ_A = 73.7⁰)-SLC25A44 (Θ_M = 42.3⁰)-PMF1-BGLAP (Θ_A = 72.4⁰)-TMEM79 (Θ_A = 64.4⁰)-TSACC (Θ_M = 49.4⁰)-RHBG (Θ_M = 55.3⁰) in series from 5’ to 3’ on human ch 1q22 at positions +1 through +6 in reference to LMNA. As shown is an anisotropic gene within its hypotenusal gene intergene base distance tropy positioned at angulation, Θ_A ≤ 82.3⁰ in the z, y-vertical plane with Σ gene + intergene base distance, d_A· sin Θ_A, juxtaposed to a mesotropic gene within its hypotenusal gene intergene base distance tropy positioned at angulation, Θ_M ≥ 11.7⁰, from the horizontal line of unity in a heterochromatin strand amorphous form loop segment. A transcribable gene can be either an anisotropic segment loop gene (Θ_A) or a mesotropic gene segment loop gene (Θ_M) in an amorphous segment loop of alternating in-tandem genes. Legend. d_A, hypotenusal distance of anisotropic gene intergene tropy bases; d_M, hypotenusal distance of mesotropic gene intergene tropy bases. Note: 3’, downstream