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Fig. 3 | Translational Medicine Communications

Fig. 3

From: Anglemetry of neural axis cell differentiation genes by structural pressurotopy of DNA loop strand segment tropy in reference to tissue macro-compliance

Fig. 3

Angulation of intergene base arc distance tropy in reference to the z, x-axis horizontal plane mesotropic heterochromatin loop segment genes. Mesotropic heterochromatin strand loop micro-structural arrangement is a series of ≥ 3 intergene base distance-separated genes perceiving the lesser grade asymmetric tropy viscosity effect with nano-compliance of the same, ΘM. RNA/ncRNA class gene locus ENSG00000224276 / LOC105371729 (Peff, 0.260)-containing mesotropic form heterochromatin strand loop segment consisting of three genes in-series is arranged as ENSG00000224276 / LOC105371729 (ΘM = 58.60)-GC01P156042 (LAMTOR2) (ΘM = 58.70)-RAB25 (ΘM = 57.40) from 5’ to 3’ on the forward (+) strand of human ch 1q22 at positions -3 through -1 in reference to LMNA; and the heavy chain immunoglobin gene locus (IGH_) containing mesotropic form heterochromatin strand loop segment consisting of 8 diversity genes in-series is arranged as IGHD1-20 (nf) (ΘM = 410)-IGHD6-19 (ΘM = 52.70)-IGHD5-18 (ΘM = 59.30)-IGHD4-17 (ΘM = 52.50)-IGHD3-16 (ΘM = 52.80)-IGHD2-15 (ΘM = 54.50)-IGHD1-14 (ΘM = 54.70)-IGHD6-13 (ΘM = 55.40) from 3’ to 5’ on the reverse (-) strand of human ch 14q32.3 in native configuration. As shown is a gene of a mesotropic heterochromatin segment loop positioned at the lower limit of angulation ΘM = 11.70 in the z, y-vertical plane that horizontally aligns for transcription in z, x-axis at a Peff of 0.648 esebssiwaagoTQ units. Legend. ΘH, zero degree horizontal; dM, hypotenusal distance of anisotropic gene intergene tropy bases; dM sin ΘM, distance to horizontal for anisotropic gene intergene tropy distance; dM at H0 = 00, dM·cos ΘM + xM; Peffective intracellular pressure (Peff) = Peffective intranuclear pressure

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