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Table 2 Angulation of anisotropic genes in reference to the horizontal for the linear normal esebssiwaagoTQ effective intracellular pressure unit

From: Anglemetry of neural axis cell differentiation genes by structural pressurotopy of DNA loop strand segment tropy in reference to tissue macro-compliance

Gene (no. of locus bases; no. of gene bases or n/a)

Gene locus (strand)

Episode category (final SEB structure)

sebs f(x)a

sebssiwa f(x)a

bsebs/bsebssiwab

sebs – sebssiwa (x1, y1; x2, y2), residual

uppesebssiwaa, dppesebssiwaa (Peff esebssiwaagoTQ)

Angulation (0)

MIR4537, microRNA 4537

(70; n/a)

14q32.3 (−)

3 A 7

5.799E+ 03

e8E-03x

1.424E+ 03

e1.72E+02x

4.07

4,821, 114,933;

4,422, 8,770

1,942, 30,195

(0.064c)

82.3

COL2A1, collagen type VI alpha 1 chain

(23,314; n/a)

12q13.11 (−)

2 A 5

6.1920E+ 04 e3E-07x

3.2569E+ 04 e1E-07x

1.90

61,839, 927,330; 32,304, 73,115

31,611, 268,390

(0.118)

75.8

RGS4, regulator of g protein signaling 4

(8,197; n/a)

1q23.3 (+)

3 M 7

7.8415E+ 04

e-2E-07x

2.5014E+ 04

e2E-07x

3.14

54,373, 797,384; 75,774, 139,206

26,223, 222,547

(0.118)

75.8

MYC, MYC proto-oncogene

(6,001; n/a)

8q24.21 (+)

3 A 5

8.8964E+ 04 e3E-08x

2.4479E+ 04 e2E-06x

3.63

58,846, 695,321; 42,913, 113,936

36,168, 230,798

(0.157)

71

CCN2, cellular communication network factor 2

(3,203; n/a)

6q23.2 (−)

3 A 8

1.21063E+05

e3E-09x

3.0266E+04

e1E-08x

4.00

91,067, 837,824;

90,880, 256,983

30,325, 182,468

(0.166)

70

LMNB2, lamin B2

(288,491; 29,359)

19q13.3 (−)

4 A 7

3.0747E+04

e7E-07x

1.1944E+04

e9E-06x

2.57

18,824, 220,250;

19,549,

45,732

8,024, 48,141

(0.167)

69.8

ESRRB, Estrogen Related Receptor Beta

(196,759; 191,128)

14q24.3 (+)

2 A 5

1.05918E+04

e1E-06x

3.4501E+04

e2E-06x

3.07

64,086, 539,533; 22,161, 45,003

27,102, 157,268

(0.172)

69.2

LMNA, lamin A/C

(57,934; 57,544)

1q22 (+)

2 A 5

6.65237E+05

e2E-05x

1.92333E+05 e6E-06x

3.46

28,935, 382,265;

43,439,

123,966

28,945, 157,549 (0.184)

67.8

LMNB1, lamin B1

(60,398; n/a)

5q23.2 (+)

2 A 5

1.0E+05

e5E-07x

2.96910E+05 e1E-05x

3.37

32,013, 478,625; 58,014, 135,885

37,010, 187,599

(0.197)

66.2

EGR1, early growth response 1

(3,826; n/a)

5q31.2 (+)

3 M 7

7.93682E+05

e5E-06x

4.04638E+05

e4E-05x

1.96

18,244, 199,860; 39,226 88,802

28,735, 144,331

(0.199)

66.0

PRKCH, protein kinase C eta type

(471,621; 363,422)

14q32.2 (+)

4 A 5

2.0E+06

e1E-05x

3.86798E+05

e1E-05x

5.17

35,062, 628,017; 76,455, 155,817

46,994, 234,912

(0.200)

65.8

IER3, immediate early response 3

(1,356; n/a)

6q21.33 (−)

3 M 5

6.75603E+05

e2E-05x

3.08411E+05

e9E-06x

2.78

11,982, 102,979; 35,375, 84,093

14,835, 72,513

(0.205)

65.3

EMD,

emerin

(2,327; n/a)

Xq28 (+)

3 A 5

2.70939E+05

e4E-06x

8.5425E+04

e3E-06x

3.17

7,078, 172,964; 39,612, 98,034

21,576,92,258 (0.234)

61.7

COL6A1, collagen type VI alpha 1 chain

(23,314; n/a)

21q22.3 (+)

2 A 4 q term

7.1790E+04 e1E-05x

3.5895E+04 e3E-05x

2.00

807, 36,660; 23,271, 65,941

12,039, 51,301

(0.235)

61.6

COL1A1, collagen type I alpha 1 chain

(18,360; n/a)

17q21.33 (−)

2 A 5

3.1489E+04

e9E-07x

1.5175E+04

e6E-06x

2.08

20,066, 140,511; 13,062, 25,468

11,547,47,862 (0.241)

60.9

  1. af(x) = b·em·x, where b is the downstream anisotropic effect (intercept and slope are absolute values); bbsebs/bsebssiwa is the linearization quotient; and cpreviously reported episode and sub-episode block structure and esebssiwaagoTQ value as per references, MIR4537 [26, 27]. Note: 1) Gene loci sub-episode block structure (SEB) variations include non-contributory anisotropy (NCA), anisotropy converted to mesotropy (ACM), and/or 0.5-factor adjusted stabilizing mesotropy or anisotropy converted to stabilizing isotropy for anisotropy or mesotropy (stIAfM, stIMfA or stIMfM) that result in an initial to final SEB conversion; 2) Sub-episode block structures for initial to final SEB converted genes are MYC, 3 A 7 (−2); CCN2, 3 A 7 (+1) stIAfA; LMNB2, 4 A 9 (−2) NCA; PRKCH, 4 A 9 (−2) (−2) NCA ACM; COL6A1, 2 A 5 (−1) q terminal end; IER3, 3 M 7 (− 2) ACM; and EMD, 3 A 7 (− 2) stIAfA; and 3) bsebs/bsebssiwa for MIR4357, COL2A1, RGS4, MYC, CCN2, LMNB2, ESRRB and COL1A1 is by reverse x-intercept plotting of the uppasebs, uppamsebs, dppasebs and dppmsebs and the corelate uppasebssiwa, uppamsebssiwa, dppasebssiwa and dppmsebssiwa; and the same for LMNA and PRKCH is by x-, y- function bsebs and bsebssiwa intercept hybridization