Fig. 5

The protein-protein interaction network analysis tool (STRING database) was used to analyze the proteins identified in the fractions of Mycoplasma fermentans MFI cultured in anaerobic (a) and aerobic (b) conditions. A network was build based on medium confidence (0.4) evidence. Proteins are indicated by nodes labeled with the gene symbol. The network was enriched in interactions, using the intersection of 10 additional proteins that were labeled as white nodes in the figure. Mycoplasma hominis was used as reference genome. The proteins labeled with the symbol ‘=’ are present both in anaerobiosis and aerobiosis. a: represents the fraction of MFI cultured in anaerobic conditions showing 246 interactions between individual proteins (or nodes). In the analysis, STRING did not include the following proteins: argF, malL, xfp, p37 and pmpr (exclusive of anaerobic MFI) abca, ptsI, pdhA, nrnA and hysA (commonly present in both anaerobic and aerobic MFI). b: shows the fraction of MFI cultured in aerobic conditions depicting 212 interactions between individual proteins. In the analysis, STRING did not include the following proteins: had, kduI, ndt, rlmb and pstb (exclusive of aerobic MFI), abca, ptsI, pdhA, nrnA, and hysA (commonly present in both anaerobic and aerobic MFI)