Table 1 Listing of the 40 genes identified by IGNITE member PIs and each gene’s CPIC Level of Evidence. Genes with Medicare/Medicaid reimbursement are identified with a^a

A

CYP2C19^a, CYP2C9^a, CYP2D6^a, CYP3A5, CYP4F2, DPYD, G6PD, HLA A 31 01, HLA B 15 02^b, HLA B 57 01, HLA B 58 01, IFNL3, SLCO1B1, TPMT, UGT1A1, VKORC1^a

16

B

CYP2B6

1

C

CYP3A4, DRD2, MTHFR

3

C/D

ABCB1, CYP2C8, OPRM1

3

D

HTR2A, HTR2C

2

No CPIC rating

ABCC2, ABCC3, ABCC4, CYP2C cluster rs12777823, DRD1, FAAH, GRIN2A, ITPA, NUDT15, OCT1, SLC6A4, SV2C, UGT1A9, UGT2B15, UGT2B7

15