Variables | Cryothermia (n = 20) | RF (n = 21) | p Value* Cryo vs. RF | No-maze (n = 19) | p Value* No-maze vs. Cryo | p Value* No-maze vs. RF | p Value** |
---|---|---|---|---|---|---|---|
Tn-T (ng/L) | |||||||
Preoperative | 12.5 [8.5–17] | 12 [9–16] | 15 [11–17] | 0.53 | |||
T0 | 8145 [5095–14,440] | 2140 [1900–3290] | 0.002 | 709 [517–786] | < 0.001 | 0.002 | < 0.001 |
T3 | 12,805 [6140–15,700] | 2790 [1880–4180] | 0.002 | 999 [683–1420] | < 0.001 | 0.002 | < 0.001 |
T20 | 3400 [2785–4900] | 1980 [1640–2530] | 0.01 | 798 [565–929] | < 0.001 | 0.001 | < 0.001 |
Postoperative day 3 | 2095 [1645–3275] | 1200 [1030–1670] | 0.005 | 576 [437–754] | < 0.001 | 0.01 | < 0.001 |
CK-MB (μg/L) | |||||||
Preoperative | 2 [1.5–2.5] | 2 [1–3] | 2 [2–3] | 0.99 | |||
T0 | 269 [243–352] | 68 [62–81] | < 0.001 | 47 [34–59] | < 0.001 | 0.06 | < 0.001 |
T3 | 271 [217–357] | 79 [66–93] | < 0.001 | 48 [32–71] | < 0.001 | 0.09 | < 0.001 |
T20 | 107 [69–132] | 53 [42–57] | 0.005 | 29 [18–43] | < 0.001 | 0.02 | < 0.001 |
ASAT (μg/L) | |||||||
Preoperative | 0.5 [0.4–0.5] | 0.5 [0.4–0.5] | 0.5 [0.4–0.6] | 0.58 | |||
T0 | 2.5 [1.8–3.9] | 2.4 [1.8–3.4] | 1.0 | 1.2 [0.9–1.5] | < 0.001 | 0.001 | < 0.001 |
T3 | 3.3 [2.5–5.9] | 2.9 [2–4.1] | 0.55 | 1.3 [1.1–1.7] | < 0.001 | < 0.001 | < 0.001 |
T20 | 3.3 [2.5–3.8] | 2.2 [2–2.6] | 0.006 | 1.3 [1.0–1.6] | < 0.001 | 0.01 | < 0.001 |
ALAT (μg/L) | |||||||
Preoperative | 0.4 [0.3–0.5] | 0.4 [0.4–0.5] | 0.4 [0.3–0.5] | 0.64 | |||
T20 | 0.5 [0.4–0.7] | 0.5 [0.4–0.6] | 0.5 [0.3–0.6] | 0.16 | |||
CRP (mg/L) | |||||||
Preoperative | 0.9 [0.4–1.9] | 1.7 [0.7–3.9] | 0.40 | 2.8 [1.5–7.2] | 0.01 | 0.38 | 0.01 |
T20 | 77 [63–86] | 75 [52–104] | 77 [60–87] | 0.89 | |||
IL-6 (NPX) | |||||||
ΔT0-Preoperative | 300 [221–510] | 185 [121–365] | 193 [137–386] | 0.23 | |||
ΔT3-Preoperative | 223 [159–333] | 141 [106–279] | 206 [112–317] | 0.20 | |||
ΔT20-Preoperative | 150 [82–332] | 120 [85–193] | 222 [135–433] | 0.09 | |||
IL-18 (NPX) | |||||||
ΔT0-Preoperative | −38 [−65 - -19] | −37 [−64–6] | −50 [−60 - -23] | 0.87 | |||
ΔT3-Preoperative | −5 [−34–9] | −38 [−45 - -3] | −10 [−29 - -3] | 0.32 | |||
ΔT20-Preoperative | −11 [−33 - -1] | −12 [− 34–7] | −28 [− 64–3] | 0.47 | |||
STK4 (MST1) (NPX) | |||||||
ΔT0-Preoperative | −4.0 [−7.1 - -0.1] | −2.6 [− 12.0 - -1.0] | −5.0 [−8.6 - − 3.1] | 0.5 | |||
ΔT3-Preoperative | -3.1 [−5.9 - -0.7] | −6.9 [−10.2 - -2.9] | −5.3 [− 7.0 - -1.7] | 0.06 | |||
ΔT20-Preoperative | −6.6 [−8.5 - -2.4] | − 6.1 [−11.2 - -3.1] | − 8.1 [−10.5 - -3.8] | 0.6 | |||
PAR-1 (NPX) | |||||||
ΔT0-Preoperative | −5.0 [−10.3–17.0] | 2.2 [−15.6–16.2] | −7.3 [−18.6–5.6] | 0.3 | |||
ΔT3-Preoperative | 7.8 [0.1–17.6] | −9.8 [−19.3–0.1] | 0.002 | −5.0 [−14.6–4.8] | 0.08 | 0.9 | 0.003 |
ΔT20-Preoperative | −8.1 [− 18.8–8.0] | −17.0 [−21.8–4.0] | − 15.7 [−26.8 - -9.4] | 0.3 | |||
HSP27 (NPX) | |||||||
ΔT0-Preoperative | 259 [98–310] | 151 [−35–330] | 0.6 | 106 [− 133–174] | 0.03 | 0.6 | 0.04 |
ΔT3-Preoperative | 196 [129–278] | 42 [− 181–156] | 0.02 | −26 [−115–98] | 0.001 | 1.0 | 0.007 |
ΔT20-Preoperative | −40 [− 204–81] | −87 [− 301–80] | − 138 [− 271 - -23] | 0.3 | |||
TRAIL-R2 (NPX) | |||||||
ΔT0-Preoperative | 6.6 [2.7–13.7] | 8.7 [7.0–21] | 4.2 [2.5–11.3] | 0.2 | |||
ΔT3-Preoperative | 27 [21–38] | 23 [17–31] | 20 [17–37] | 0.1 | |||
ΔT20-Preoperative | 25 [19–33] | 25 [15–40] | 25 [16–40] | 0.9 | |||
NT-proBNP (ng/L) | |||||||
Preoperative | 1250 [730–1945] | 1380 [950–1910] | 1620 [1220–3120] | 0.65 | |||
T20 | 5290 [3295–10,615] | 5470 [3060–9250] | 3730 [2750–5810] | 0.48 | |||
Postoperative day 3 | 6105 [4300–9185] | 6000 [3990–11,200] | 5430 [3660–14,000] | 0.99 |