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Fig. 9 | Translational Medicine Communications

Fig. 9

From: In vivo optical endomicroscopy: two decades of translational research towards next generation diagnosis of eosinophilic esophagitis

Fig. 9

Milestone 7: µOCT enables maintenance of high lateral imaging resolutions over an extended DOF. a low NA vs. high NA imaging with regards to lateral resolution (Δx) and DOF (b). b DOF extension using coaxially focused multi-mode (CAFM) beam. Simulation results of the intensity profile over depth as well as real transverse beam profiles of both a Gaussian and a CAFM beam are depicted. c µOCT images of esophageal swine tissue ex vivo compared to those obtained by conventional probe optics (figure and caption adapted and reprinted with permission from [133] © The Optical Society)

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