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Table 4 The laboratory follow-up of COVID-19 Patients During the Monitoring Period. Abu Dhabi, 2020

From: Safety and efficacy of autologous non-hematopoietic enriched stem cell nebulization in COVID-19 patients: a randomized clinical trial, Abu Dhabi 2020

Variables

PB-NHESC-C treated

Control

p-valueb

Time

n

Median (95% CI)

p-valuea

n

Median (95% CI)

p-valuea

White blood cells (109/L)

1st

51

6.8 (4, 20.45)

0.5377

35

6.855 (3.199, 13.45)

0.0753

0.0174*

2nd

7.6 (3.84, 18.76)

10.99 (4.006, 24.5)

Neutrophils (109/L)

1st

51

4.4 (1.6, 17.75)

0.2251

35

4.49 (1.812, 12)

0.3023

0.0029**

2nd

4.3 (1.5, 15.18)

7.27 (2.21, 22.65)

Lymphocytes (109/L)

1st

51

1.305 (0.55, 3.2)

< 0.0001***

35

1.305 (0.5205, 3.46)

0.068

0.0017**

2nd

2.1 (0.802, 3.38)

1.64 (0.38, 2.758)

Monocytes (109/L)

1st

51

0.6 (0.3, 1.25)

0.9838

35

0.535 (0.1355, 1.078)

0.0017**

0.019*

2nd

0.6 (0.3, 1.504)

0.88 (0.302, 1.852)

Eosinophils (109/L)

1st

51

0.1 (0, 0.3)

< 0.0001***

35

0.075 (0.00, 0.4155)

0.0074**

0.3378

2nd

0.2 (0, 0.82)

0.18 (0.00, 0.81)

Basophils (109/L)

1st

51

0.0 (0, 0.1)

< 0.0001***

35

0.02 (0.00, 0.0645)

0.0109*

0.3925

2nd

0.1 (0, 0.2)

0.03 (0.00, 0.158)

NLR (U)

1st

51

3 (0.86, 15.66)

0.0011**

35

2.6 (0.84, 15.7)

0.5764

< 0.0001***

2nd

1.8 (0.56, 16.79)

4.3 (1.1, 57.66)

D-Dimer (μg FEU/mL)

1st

49

0.4 (0.2, 8.1)

0.1113

31

0.57 (0.21, 14.8)

0.3931

< 0.0001***

2nd

0.2 (0, 3.6)

1.51 (0.26, 537.7)

Fibrinogen (g/dL)

1st

31

718 (380, 1136)

< 0.0001***

13

420 (240, 1940)

0.0625

< 0.0001***

2nd

350 (220, 69)

470 (390, 980)

IL-6 (pg/mL)

1st

31

20.3 (1.5, 3361)

< 0.0001***

0

ND

ND

ND

2nd

3.05 (1.4, 3384)

ND

C-reactive protein (mg/L)

1st

31

34 (0.6, 381.8)

< 0.0001***

24

21.79 (0.4, 335.3)

0.0049**

0.0048**

2nd

3.6 (0.42, 111)

16.45 (0.6, 350)

  1. Time: comparing 1st and 2nd studies inside each group; n: sample size; NLR: neutrophil/lymphocyte ratio; ND: not determined; 95% CI: Confidence interval; a: Wilcoxon test for nonparametric pair samples; b: Mann-Whitney U test, comparing the two groups; *: significant difference; **: higly significant; ***: very higly significant