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Fig. 3 | Translational Medicine Communications

Fig. 3

From: AMP5A modulates Toll-like receptors 7 and 8 single-stranded RNA immune responses in PMA-differentiated THP-1 and PBMC

Fig. 3

AMP5A % inhibition of CXCL10 release in THP-1 and PBMC. Box plots for 24-hour 5 µg/ml CL075-induced CXCL10 release and AMP5A percent inhibitions for PMA-differentiated THP-1 cells and PBMC. Data presented as CL075-induced CXCL10 pg/ml release for both saline- and AMP5A-treatment groups from PMA-differentiated THP-1 (A) or PBMC (B) as well as percent inhibitions in CXCL10 release observed in the AMP5A-treatment groups calculated versus saline-treated controls (C). Boxes = quartile 1 to 3 boundaries, line = Median, + = Mean. For THP-1, n = 8 independent experiments. For PBMC, n = 9 independent experiments using cells derived from a total of 7 different donors

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