Table 2 UniProtKB search results of anticancer eukaryotic ribonucleases
From: Promises of eukaryotic ribonucleases for cancer treatment: a systematic review
No | Entry name | Protein names | Accession No | Gene names | Length | Active site position | Annotation score (1–5) | Organism | |
|---|---|---|---|---|---|---|---|---|---|
Proton Acceptor | Proton Donor | ||||||||
1 | RNP30_LITPI | P-30 Protein (Onconase) | EC 3.1.27 | - | 104 | 4 | Lithobates pipiens (Northern leopard frog) (Rana pipiens) | ||
2 | Q8UVX5_LITPI | Onconase variant rpr | - | rpr | 127 | - | - | - | Lithobates pipiens (Northern leopard frog) (Rana pipiens) |
3 | Q9I8V8_LITPI | Onconase variant rapLR1 | - | - | 127 | - | - | - | Lithobates pipiens (Northern leopard frog) (Rana pipiens) |
4 | RNASO_LITCT | Oocytes ribonuclease (RC-RNase) (Sialic acid-binding lectin) | EC 3.1.27 | RCR | 133 | 32 | 125 | 5 | Lithobates catesbeianus (American bull frog) (Rana catesbeiana) |
5 | AMPS1_LITPI | Amphinase-1 | EC 3.1.27 | - | 114 | 15 | 107 | 4 | Lithobates pipiens (Northern leopard frog) (Rana pipiens) |
6 | AMPS2_LITPI | Amphinase-2 | EC 3.1.27 | - | 114 | 15 | 107 | 4 | Lithobates pipiens (Northern leopard frog) (Rana pipiens) |
7 | AMPS3_LITPI | Amphinase-3 | EC 3.1.27 | - | 114 | 15 | 107 | 4 | Lithobates pipiens (Northern leopard frog) (Rana pipiens) |
8 | AMPS4_LITPI | Amphinase-4 | EC 3.1.27 | - | 114 | 15 | 107 | 4 | Lithobates pipiens (Northern leopard frog) (Rana pipiens) |
9 | RNAS1_BOVIN | Ribonuclease pancreatic (RNase A) | EC 4.6.1.18 | RNASE1 RNS1 | 150 | 38 | 145 | 5 | Bos taurus (Bovine) |
10 | RNS_BOVIN | Seminal ribonuclease (S-RNase) | EC 4.6.1.18 | SRN | 150 | 38 | 145 | 5 | Bos taurus (Bovine) |
11 | ANG1_BOVIN | Angiogenin-1 | EC 3.1.27 | ANG1 ANG | 148 | 37 | 139 | 5 | Bos taurus (Bovine) |
12 | ANGI_HUMAN | Angiogenin (RNase 5) | EC 3.1.27 | ANG RNASE5 | 147 | 37 | 138 | 5 | Homo sapiens (Human) |
13 | RNAS1_HUMAN | Ribonuclease pancreatic (HP-RNase) | EC 4.6.1.18 | RNASE1 RIB1 RNS1 | 156 | 40 | 147 | 5 | Homo sapiens (Human) |
14 | ECP_HUMAN | Eosinophil cationic protein (ECP) | EC 3.1.27 | RNASE3 ECP RNS3 | 160 | 42 | 155 | 5 | Homo sapiens (Human) |
15 | Q6FHX6_HUMAN | Flap endonuclease 1 (FEN-1) | EC 3.1 | FEN1 hCG_40848 | 380 | - | - | 4 | Homo sapiens (Human) |
16 | RNMC_MOMCH | Ribonuclease MC (RNase MC) | EC 4.6.1.19 | - | 191 | 34 | 85 | 2 | Momordica charantia (Bitter gourd) (Balsam pear) |
17 | V5UTC6_LENED | Latcripin-16 | Latcripin-16 | - | 131 | - | - | 1 | Lentinula edodes (Shiitake mushroom) (Lentinus edodes) |
18 | F8WSJ0_LYOSH | Ribonuclease T(2) (Fragment) | EC 4.6.1.19 | RNLs30 | 310 | - | - | 2 | Lyophyllum shimeji (Hon-shimeji) (Tricholoma shimeji) |
19 | G3XZU9_ASPNA | Ribonuclease | EC 3.1.26.4 | ASPNIDRAFT_209236 | 352 | - | - | 2 | Aspergillus niger (strain ATCC 1015) |
20 | A0A2U7NFE7_WHEAT | Dicer-like protein (Fragment) | Dicer-like protein | dcl4 | 1392 | - | - | 2 | Triticum aestivum (Wheat) |