Fig. 5From: Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine gliomaImmunofluorescent PEG staining on sagittal slices of FUS-treated mouse brains. A positive staining of liposomes (in green) was detected in the pontine region of control (non-tumor bearing mice) (upper panel) who received Caelyx®. The pontine/tumor area delineated with a yellow dotted line. In contrast, only few liposomes were observed in the blood vessels of the HSJD-DIPG-07 xenograft model that received Caelyx® (lower panel). In both panels endothelial cells are indicated in red (CD31 staining), nuclei in blue (DAPI)Back to article page