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Fig. 5 | Translational Medicine Communications

Fig. 5

From: Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine glioma

Fig. 5

Immunofluorescent PEG staining on sagittal slices of FUS-treated mouse brains. A positive staining of liposomes (in green) was detected in the pontine region of control (non-tumor bearing mice) (upper panel) who received Caelyx®. The pontine/tumor area delineated with a yellow dotted line. In contrast, only few liposomes were observed in the blood vessels of the HSJD-DIPG-07 xenograft model that received Caelyx® (lower panel). In both panels endothelial cells are indicated in red (CD31 staining), nuclei in blue (DAPI)

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