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Fig. 4 | Translational Medicine Communications

Fig. 4

From: Targeting EphA2 and DDR signaling can overcome the BRAF and MEK inhibitors acquired resistance in melanoma cell lines

Fig. 4

Effects of ALW‑II‑41‑27 treatment on invasion and migration in vemurafenib and/or cobimetinib-resistant melanoma cell lines. Parental and resistant cell lines were treated with 0,5 µM of ALW‑II‑41‑27for 48 h. A Cell invasion ability was evaluated by the Transwell invasion assay. B Graph bar showing the invasion capability of melanoma cancer cell lines untreated and after treatment. C Cell migration capability was measured by the wound-healing assay. D Graph bar showing the migration capability of melanoma cancer cell lines untreated and after treatment. **: P < 0.001; ***: P < 0,0005

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Translational Medicine Communications

ISSN: 2396-832X

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