Patient characteristics | HIF-1α | p-value | VEGFA | p-value | HK1 | p-value | ||||
---|---|---|---|---|---|---|---|---|---|---|
Low | High | Low | High | Low | High | |||||
Age | ≤ 50 | 11 | 20 | 0.343 | 8 | 23 | 0.608 | 13 | 18 | 0.295 |
> 50 | 12 | 13 | 5 | 20 | 14 | 11 | ||||
Histological Subtype | Ductal | 16 | 24 | 0.276 | 13 | 27 | 0.559 | 17 | 23 | 0.954 |
Lobular | 2 | 2 | 1 | 3 | 2 | 2 | ||||
Others | 2 | 10 | 2 | 10 | 5 | 7 | ||||
Family History | Yes | 1 | 5 | 0.344 | 2 | 4 | 0.534 | 3 | 3 | 0.852 |
No | 18 | 32 | 11 | 39 | 23 | 27 | ||||
Lymph Node | Positive | 10 | 23 | 0.311 | 9 | 24 | 0.921 | 15 | 18 | 0.415 |
Negative | 10 | 13 | 6 | 17 | 13 | 10 | ||||
Grade | I | 2 | 5 | 0.834 | 2 | 5 | 0.159 | 5 | 2 | 0.296 |
II | 11 | 17 | 11 | 17 | 12 | 16 | ||||
III | 7 | 14 | 3 | 18 | 8 | 13 | ||||
Subtypes ER, PR,Her2 | + + + | 6 | 2 | 0.097 | 3 | 5 | 0.259 | 5 | 3 | 0.036 |
+ + - | 12 | 13 | 11 | 14 | 16 | 9 | ||||
3 | 9 | 2 | 10 | 2 | 10 | |||||
- - - | 3 | 8 | 2 | 9 | 4 | 7 | ||||
Menopausal | No | 10 | 14 | 0.528 | 8 | 16 | 0.266 | 10 | 14 | 0.393 |
Yes | 10 | 20 | 6 | 24 | 16 | 14 | ||||
Necrosis | Absent | 12 | 18 | 0.861 | 7 | 23 | 0.351 | 18 | 12 | 0.029 |
Present | 11 | 15 | 9 | 17 | 8 | 18 | ||||
Stage | I | 3 | 4 | 0.631 | 2 | 5 | 0.933 | 5 | 2 | 0.406 |
II | 9 | 21 | 8 | 22 | 13 | 17 | ||||
III | 8 | 11 | 6 | 13 | 9 | 10 |