Fig. 4

Confusion matrix analyzing the time and concentration variability of the pharmacokinetics of various brain regions when the catheter tip is placed at C1 (A) or T10 (B). Each matrix demonstrates the average value across the cohort and the color bar represents the Pearson correlation coefficients. Due to the symmetric nature of the cross-correlation analysis between ROI-pairs, the lower half of each matrix was not included. A value of 1 along the x-axis denotes regions of highest similarity, while a value of 0 denotes regions of least similarity