Category | GO ID | Description | Gene Count | P-value |
---|---|---|---|---|
a. Human top 10 ranked GO and KEGG terms | ||||
 GO:MF | GO:0005201 | Extracellular matrix structural constituent | 31 | 2.934 × 10−16 |
 GO:MF | GO:0005198 | Structural molecule activity | 56 | 5.755 × 10−13 |
 GO:MF | GO:0005515 | Protein binding | 405 | 3.072 × 10−10 |
 GO:MF | GO:0019838 | Growth factor binding | 22 | 6.965 × 10−10 |
 GO:MF | GO:0005102 | Signalling Receptor binding | 85 | 6.875 × 10− 9 |
 GO:MF | GO:0008307 | Structural constituent of muscle | 12 | 1.147 × 10−7 |
 GO:MF | GO:0048407 | Platelet-derived growth factor binding | 7 | 6.545 × 10−7 |
 GO:MF | GO:0003779 | Actin binding | 33 | 4.224 × 10−6 |
 GO:MF | GO:0030020 | Extracellular matrix structural constituent conferring tensile strength | 10 | 1.576 × 10−5 |
 GO:MF | GO:0005539 | Glycosaminoglycan binding | 22 | 2.948 × 10−5 |
 GO:BP | GO:0072359 | Circulatory system development | 125 | 4.102 × 10−42 |
 GO:BP | GO:0009888 | Tissue development | 164 | 3.639 × 10−40 |
 GO:BP | GO:0009653 | Anatomical structure morphogenesis | 190 | 1.027 × 10− 39 |
 GO:BP | GO:0007507 | Heart development | 87 | 1.102 × 10− 39 |
 GO:BP | GO:0048856 | Anatomical structure development | 286 | 3.192 × 10− 36 |
 GO:BP | GO:0048513 | Animal organ development | 213 | 4.501 × 10− 35 |
 GO:BP | GO:0007275 | Multicellular organism development | 269 | 3.918 × 10−34 |
 GO:BP | GO:0032502 | Developmental process | 295 | 1.495 × 10− 33 |
 GO:BP | GO:0048731 | System development | 251 | 5.654 × 10−33 |
 GO:BP | GO:0032501 | Multicellular organismal process | 325 | 1.979 × 10−32 |
 GO:CC | GO:0031012 | Extracellular matrix | 65 | 4.532 × 10− 24 |
 GO:CC | GO:0062023 | Collagen-containing extracellular matrix | 52 | 4.427 × 10− 20 |
 GO:CC | GO:0043292 | Contractile fiber | 40 | 7.417 × 10− 20 |
 GO:CC | GO:0030016 | Myofibril | 36 | 7.681 × 10−17 |
 GO:CC | GO:0030017 | Sarcomere | 34 | 1.992 × 10−16 |
 GO:CC | GO:0099081 | Supramolecular polymer | 69 | 6.482 × 10−13 |
 GO:CC | GO:0099512 | Supramolecular fiber | 68 | 1.488 × 10−12 |
 GO:CC | GO:0005788 | Endoplasmic reticulum lumen | 35 | 5.127 × 10−12 |
 GO:CC | GO:0031674 | I band | 23 | 1.046 × 10−10 |
 GO:CC | GO:0099080 | Supramolecular complex | 75 | 7.206 × 10−10 |
 KEGG | KEGG:04512 | ECM-receptor interaction | 15 | 2.194 × 10−6 |
 KEGG | KEGG:04510 | Focal Adhesion | 20 | 9.739 × 10−5 |
 KEGG | KEGG:04350 | TGF-beta signaling pathway | 13 | 2.084 × 10−4 |
 KEGG | KEGG:05414 | Dilated cardiomyopathy | 13 | 2.664 × 10−4 |
 KEGG | KEGG:04550 | Signaling pathways regulating pluripotency of stem cells | 16 | 2.869 × 10−4 |
 KEGG | KEGG:04260 | Cardiac muscle contraction | 12 | 5.994 × 10−4 |
 KEGG | KEGG:04974 | Protein digestion and absorption | 13 | 6.676 × 10−4 |
 KEGG | KEGG:05410 | Hypertrophic cardiomyopathy | 12 | 8.583 × 10−4 |
 KEGG | KEGG:04151 | PI3K-Akt signaling pathway | 25 | 2.335 × 10−3 |
 KEGG | KEGG:04261 | Adrenergic signaling in cardiomyocytes | 13 | 3.488 × 10−2 |
b. Mouse top 10 ranked GO and KEGG terms. | ||||
 GO:MF | GO:0004308 | Exo-alpha-sialidase activity | 4 | 1.652 × 10−3 |
 GO:MF | GO:0016997 | Alpha-sialidase activity | 4 | 1.652 × 10−3 |
 GO:MF | GO:0052794 | Exo-alpha-(2- > 3)-sialidase activity | 4 | 1.652 × 10−3 |
 GO:MF | GO:0052795 | Exo-alpha-(2- > 6)-sialidase activity | 4 | 1.652 × 10−3 |
 GO:MF | GO:0052796 | Exo-alpha-(2- > 8)-sialidase activity | 4 | 1.652 × 10−3 |
 GO:MF | GO:0008138 | Protein tyrosine/serine/threonine phosphatase activity | 10 | 5.683 × 10−3 |
 GO:BP | GO:0006689 | Ganglioside catabolic process | 5 | 4.131 × 10−3 |
 GO:BP | GO:0009313 | Oligosaccharide catabolic process | 5 | 2.322 × 10−2 |
 GO:BP | GO:0050877 | Nervous system process | 128 | 3.665 × 10−2 |
 GO:CC | GO:0005882 | Intermediate filament | 26 | 1.448 × 10−4 |
 GO:CC | GO:0045111 | Intermediate filament cytoskeleton | 26 | 3.344 × 10−3 |
 KEGG | GO:04915 | Estrogen signaling pathway | 19 | 1.095 × 10−3 |