Category | GO ID | Description | Gene Count | P-value |
---|---|---|---|---|
a. Pathway enrichment analysis to show the top 3 GO and KEGG terms of Subcluster Ha | ||||
 GO:MF | GO:0005201 | Extracellular matrix structural constituent | 15 | 1.032 × 10−18 |
 GO:MF | GO:0005198 | Structural molecule activity | 21 | 1.084 × 10−17 |
 GO:MF | GO:0030020 | Extracellular matrix structural constituent conferring tensile strength | 8 | 6.423 × 10−12 |
 GO:BP | GO:0006936 | Muscle contraction | 19 | 3.864 × 10−19 |
 GO:BP | GO:0003012 | Muscle system process | 20 | 1.377x × 10−18 |
 GO:BP | GO:0070252 | Actin-mediated cell contraction | 13 | 5.983 × 10−18 |
 GO:CC | GO:0099081 | Supramolecular polymer | 25 | 2.044 × 10−20 |
 GO:CC | GO:0099512 | Supramolecular fiber | 24 | 5.143 × 10−19 |
 GO:CC | GO:0099080 | Supramolecular complex | 25 | 1.732 × 10−17 |
 KEGG | KEGG:04260 | Cardiac muscle contraction | 9 | 1.136 × 10−9 |
 KEGG | KEGG:05410 | Hypertrophic cardiomyopathy | 9 | 1.554 × 10−9 |
 KEGG | KEGG:05414 | Dilated cardiomyopathy | 9 | 2.554 × 10−9 |
b. Pathway enrichment analysis to show the top 3 GO and KEGG terms of Subcluster Hb | ||||
 GO:MF | GO:0008307 | Structural constituent of muscle | 4 | 1.214 × 10−4 |
 GO:MF | GO:0005102 | Signaling receptor binding | 11 | 2.258 × 10−3 |
 GO:MF | GO:0019838 | Growth factor binding | 4 | 1.264 × 10−3 |
 GO:BP | GO:0072359 | Circulatory system development | 14 | 2.763 × 10−7 |
 GO:BP | GO:0032502 | Developmental process | 24 | 1.135 × 10−5 |
 GO:BP | GO:0035019 | Somatic stem cell population maintenance | 5 | 1.171 × 10−4 |
 GO:CC | GO:0031093 | Platelet alpha granule lumen | 4 | 4.123 × 10−4 |
 GO:CC | GO:0031091 | Platelet alpha granule | 4 | 1.430 × 10−3 |
 GO:CC | GO:0030017 | Sarcomere | 5 | 1.844 × 10−3 |
 KEGG | KEGG:04933 | AGE-RAGE signaling pathway in diabetic complications | 4 | 4.815 × 10−3 |
 KEGG | KEGG:04510 | Focal adhesion | 5 | 5.074 × 10−3 |
c. Pathway enrichment analysis to show the top 3 GO and KEGG terms of Subcluster Hc | ||||
 GO:BP | GO:0016567 | Protein ubiquitination | 5 | 4.006 × 10−2 |
 GO:CC | GO:0030017 | Sarcomere | 5 | 3.883 × 10−6 |
 GO:CC | GO:0030016 | Myofibril | 5 | 6.403 × 10−6 |
 GO:CC | GO:0043292 | Contractile fiber | 5 | 8.076 × 10− 6 |
d. Pathway enrichment analysis to show the top 3 GO and KEGG terms of Subcluster Ma | ||||
 GO:MF | GO:0004930 | G protein-coupled receptor activity Transmembrane signalling receptor activity | 10 | 2.363 × 10−6 |
 GO:MF | GO:0004888 | Transmembrane signalling receptor activity | 10 | 1.200 × 10−5 |
 GO:MF | GO:0038023 | Signaling receptor activity | 10 | 2.208 × 10− 5 |
 GO:BP | GO:0007186 | G protein-coupled receptor signalling pathway | 13 | 5.287 × 10−10 |
 GO:BP | GO:0006874 | Cellular calcium ion homeostasis | 6 | 2.908 × 10−4 |
 GO:BP | GO:0055082 | Cellular chemical homeostasis | 7 | 3.336 × 10− 4 |
 GO:CC | GO:0043679 | Axon terminus | 3 | 1.745 × 10−2 |
 GO:CC | GO:0044306 | Neuron projection terminus | 3 | 2.350 × 10−2 |
 KEGG | KEGG:04080 | Neuroactive ligand-receptor interaction | 6 | 3.988 × 10−4 |
 KEGG | KEGG:04742 | Taste transduction | 3 | 1.856 × 10−2 |
e. Pathway enrichment analysis to show the top 3 GO and KEGG terms of Subcluster Mb | ||||
 GO:MF | GO:0003723 | RNA binding | 9 | 9.759 × 10−8 |
 GO:MF | GO:0003676 | Nucleic acid binding | 10 | 4.231 × 10−5 |
 GO:MF | GO:0043021 | Ribonucleoprotein complex binding | 4 | 1.366 × 10−4 |
 GO:BP | GO:0006396 | RNA processing | 9 | 2.465 × 10− 8 |
 GO:BP | GO:0008380 | RNA splicing | 7 | 3.751 × 10−7 |
 GO:BP | GO:0006397 | mRNA processing | 7 | 1.214 × 10−6 |
 GO:CC | GO:0005687 | U4 snRNP | 3 | 2.365 × 10−6 |
 GO:CC | GO:0097525 | Spliceosomal snRNP complex | 4 | 2.365 × 10−6 |
 GO:CC | GO:0030532 | Small nuclear ribonucleoprotein complex | 4 | 4.758 × 10−6 |
 KEGG | KEGG: 03040 | Spliceosome | 4 | 3.249 × 10−5 |
f. Pathway enrichment analysis to show the top 3 GO and KEGG terms of Subcluster Mc | ||||
 GO:MF | GO:0004386 | Helicase activity | 6 | 1.539 × 10−3 |
 GO:MF | GO:0017111 | Nucleoside-triphosphatase activity | 11 | 3.713 × 10−3 |
 GO:MF | GO:0016462 | Pyrophosphatase activity | 11 | 6.465 × 10−3 |
 GO:BP | GO:0006281 | DNA repair | 9 | 5.244 × 10−3 |
 GO:BP | GO:0022402 | Cell cycle process | 13 | 5.321 × 10−3 |
 GO:BP | GO:0000280 | Nuclear division | 8 | 1.472 × 10−2 |
 GO:CC | GO:0000776 | Kinetochore | 7 | 1.582 × 10−5 |
 GO:CC | GO:0005694 | Chromosome | 14 | 5.991 × 10−5 |
 GO:CC | GO:0098687 | Chromosomal region | 8 | 9.539 × 10−5 |
 KEGG | KEGG:03440 | Homologous recombination | 4 | 7.741 × 10−4 |
 KEGG | KEGG:04962 | Vasopressin-regulated water reabsorption | 3 | 3.362 × 10−2 |