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Table 1 Differences between the KIR haplotypes

From: Killer cell immunoglobulin receptor diversity and its relevance in the human host’s response to HIV infection in African populations

Characteristic

KIR haplotype A

KIR haplotype B

Gene content

KIR2DL3, KIR2DL1, KIR3DL1, KIR2DP1, KIR2DS4 and framework genes

KIR2DL2, KIR3DS1, KIR2DS1, KIR2DS2,KIR2DS5 and framework genes

Functionality

Has mainly inhibitory functions

Has both activating and inhibitory functions