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Table 1 Anthropometric and baseline laboratory values of the study population at screening

From: A novel clinical approach to evaluating changes in fat oxidation in healthy, overnight-fasted subjects

  Lean Obese p-value
  Saline Glucose Saline Lean vs. obese
Age (yr) 35.7 ± 3.9 32.0 ± 2.2 43.7 ± 3.8 0.0272
Sex (M/F) 5/3 6/2 4/4 0.2059a
Height (cm) 177.1 ± 5.7 182.2 ± 1.8 170.8 ± 4.5 0.1064
Weight (kg) 81.8 ± 4.9 75.9 ± 3.4 95.3 ± 3.9 0.0001
BMI (kg/m2) 25.7 ± 1.0 22.7 ± 1.2 32.3 ± 0.5 <.0001
Waist circumference (cm) 87.1 ± 3.7 83.3 ± 4.5 106.3 ± 4.5 0.0005
Glucose (mg/dL) 85.3 ± 1.9 84.3 ± 1.5 99.1 ± 2.4 <.0001
Insulin (ulU/mL) 61.7 ± 12.9 57.4 ± 7.9 52.9 ± 8.9 0.5917
Free Fatty Acids (mmol/L) 0.57 ± 0.06 0.26 ± 0.03 0.43 ± 0.04 0.7864
Triglycerides (mg/dL) 90.0 ± 10.6 118.7 ± 30.5 128.0 ± 15.6 0.3619
Thyroid-Stimulating Hormone (mlu/L) 2.04 + 0.38 1.69 ± 0.21 1.79 ± 0.26 0.8308
Creatine Phosphokinase (lu/L) 89.8 ± 14.2 102.6 ± 19.2 123.8 ± 19.8 0.2145
DEXA
 Total body mass (kg) 81.5 ± 6.8 76.5 ± 4.7 96.5 ± 5.7 0.0219
 Total lean mass (kg) 52.3 ± 5.2 52.8 ± 3.0 54.7 ± 4.8 0.6907
 Total fat mass (kg) 26.1 ± 2.9 20.7 ± 2.8 38.6 ± 1.8 0.0001
 Visceral adipose tissue mass (g) 742.50 ± 173.87 518.63 ± 222.32 1262.63 ± 167.13 0.012
 % Body fat 32.3 ± 3.1 26.7 ± 2.5 40.7 ± 2.1 0.003
FSIGTT
 Glucose effectiveness (SG) 0.0201 ± 0.0031 0.0205 ± 0.0043 0.0165 ± 0.0021 0.344
 Insulin sensitivity (SI) 4.9 ± 0.9 5.4 ± 0.8 3.8 ± 1.1 0.2569
 Acute insulin response to glucose (AIRg) 385.1 ± 110.8 279.0 ± 32.6 497.4 ± 177.4 0.3883
  1. Data is represented as Mean ± SEM; Bold: P (two-sample t-test) < 0.05
  2. aChi squared test