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  1. Histopathologic analysis of biopsy specimens obtained via white light endoscopy (WLE) is the gold standard for the diagnosis of several mucosal diseases in the upper gastrointestinal (GI) tract. However, this ...

    Authors: Andreas Wartak, John G. Garber, Qian Yuan, Wayne G. Shreffler, Paul E. Hesterberg, Aubrey J. Katz, Hany Osman, Hui Min Leung, Anna Gao, David O. Otuya, Catriona Grant, Joseph A. Gardecki, Norman Nishioka, Guillermo J. Tearney and Gabriela Apiou-Sbirlea

    Citation: Translational Medicine Communications 2021 6:2

    Content type: Review

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  3. This study was conceived to provide systematic data about lung mechanics during early phases of CoVID-19 pneumonia, as long as to explore its variations during prone positioning.

    Authors: Lorenzo Viola, Emanuele Russo, Marco Benni, Emiliano Gamberini, Alessandro Circelli, Luca Bissoni, Domenico Pietro Santonastaso, Giovanni Scognamiglio, Giuliano Bolondi, Luca Mezzatesta and Vanni Agnoletti

    Citation: Translational Medicine Communications 2020 5:27

    Content type: Research

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  4. Dyslipidemia often accompanies human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART). Lipid abnormalities likely contribute to increased cardiometabolic disease among people with HIV (P...

    Authors: Emily R. Bowman, Manjusha Kulkarni, Janelle Gabriel, Xiaokui Mo, Brett Klamer, Martha Belury, Jordan E. Lake, David Zidar, Scott F. Sieg, Nehal N. Mehta, Martin P. Playford, Daniel R. Kuritzkes, Adriana Andrade, Elizabeth Koss Schmidt, Christopher Taylor, Edgar T. Overton…

    Citation: Translational Medicine Communications 2020 5:26

    Content type: Research

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  5. Mycobacterium tuberculosis is known to cause latent tuberculosis infection (LTBI) in 25–50% of the cases, of whom 10–20% develop active tuberculosis (TB). Notably, no marker currently exists for judging the thera...

    Authors: Shoji Hashimoto, Hong Zhao, Michiyo Hayakawa, Koichi Nakajima, Y-h Taguchi and Yoshiki Murakami

    Citation: Translational Medicine Communications 2020 5:25

    Content type: Research

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  6. People living with HIV (PLWH) are prone to develop sub-clinical Cardiovascular (CV) disease, despite the effectiveness of combined Antiretroviral Therapy (cART). Algorithms developed to predict CV risk in the ...

    Authors: Cristian Borrazzo, Gabriella d’Ettorre, Giancarlo Ceccarelli, Massimiliano Pacilio, Letizia Santinelli, Eugenio Nelson Cavallari, Ornella Spagnolello, Valeria Silvestri, Paolo Vassalini, Carolina Scagnolari, Marco Francone, Claudio Maria Mastroianni and Iacopo Carbone

    Citation: Translational Medicine Communications 2020 5:24

    Content type: Research

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  7. Rapid Autopsy Programs offer an opportunity to collect tissue from patients immediately after death, providing critical biological material necessary to develop more effective therapies and improve patient out...

    Authors: Eliza R. Bacon, Kena Ihle, Peter P. Lee and James R. Waisman

    Citation: Translational Medicine Communications 2020 5:23

    Content type: Protocol

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  8. Cell banks are widely used to preserve cell properties as well as to record and control the use of cell lines in biomedical research. The generation of cell banks for the manufacturing of Advanced Therapy Medi...

    Authors: Unai Perpiñá, Cristina Herranz, Raquel Martín-Ibáñez, Anna Boronat, Felipe Chiappe, Verónica Monforte, Gemma Orpella-Aceret, Ester González, Myriam Olivé, María Castella, Guillermo Suñé, Álvaro Urbano-Ispizua, Julio Delgado, Manel Juan and Josep M. Canals

    Citation: Translational Medicine Communications 2020 5:22

    Content type: Research

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  9. Since the birth of Christ, in these 2019 years, the man on earth has never experienced a survival challenge from any acellular protist compared to SARS-CoV-2. No specific drugs yet been approved. The host immu...

    Authors: Kishalay Paria, Debarati Paul, Trinath Chowdhury, Smritikana Pyne, Ranadhir Chakraborty and Santi M. Mandal

    Citation: Translational Medicine Communications 2020 5:21

    Content type: Review

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  10. Absolute CD4+ T-lymphocyte counts are used in the initiation and monitoring of antiretroviral therapy in HIV-infected patients: with the increase number of HIV infected patient and the reduce number of heath c...

    Authors: Bertrand Sagnia, Rachel Kamgaing, Charles Kouanfack, Georgette Kamdem, Samuel Sosso, Edith Temgoua, Zéphyrin Tsomo, Lucille Mabouli Zoa, Charlotte Tangimpundu, Godwin Nchinda and Alexis Ndjolo

    Citation: Translational Medicine Communications 2020 5:20

    Content type: Research

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  11. Throughout the course of this Workshop, members of the advocacy community, imaging researchers, computer and measurement scientists, clinicians and policy-focused workshop attendees engaged in cross-cutting di...

    Authors: James L. Mulshine, Riccardo S. Avila, Daniel C. Sullivan, David F. Yankelevitz, Raúl San José Estépar, Laurie Fenton Ambrose, Bruce Pyenson and Carolyn R. Aldigé

    Citation: Translational Medicine Communications 2020 5:19

    Content type: Meeting report

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  12. Vanishing white matter disease (VWMD) is a rare disease caused by mutations of the guanine exchange factor eIF2B. VWMD typically presents with juvenile onset, and there are few treatments for the disease. Rece...

    Authors: Neville Ng, Mauricio Castro Cabral-da-Silva, Simon Maksour, Tracey Berg, Martin Engel, Dina M. Silva, Dzung Do-Ha, Jeremy S. Lum, Sonia Sanz Muñoz, Nadia Suarez-Bosche, Claire H. Stevens and Lezanne Ooi

    Citation: Translational Medicine Communications 2020 5:18

    Content type: Research

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  13. SARS-CoV-2 and its associated disease, COVID-19, has infected over seven million people world-wide, including two million people in the United States. While many people recover from the virus uneventfully, a s...

    Authors: William R. Hartman, Aaron S. Hess and Joseph P. Connor

    Citation: Translational Medicine Communications 2020 5:17

    Content type: Research

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  14. Translational research carries over fundamental laboratory research findings into clinical and community settings in order to ‘translate’ the findings into practice. In addition to its potential in acceleratin...

    Authors: Ajib Diptyanusa and Mubasysyir Hasanbasri

    Citation: Translational Medicine Communications 2020 5:16

    Content type: Commentary

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  15. COVID-19 is an infectious disease caused by the SARS-CoV-2 virus that can affect lung physiology encompassing a wide spectrum of severities, ranging from asymptomatic and mild symptoms to severe and fatal case...

    Authors: Carla J. Goldin, Ramiro Vázquez, Fernando P. Polack and Damian Alvarez-Paggi

    Citation: Translational Medicine Communications 2020 5:15

    Content type: Review

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  16. Patients with rheumatoid arthritis (RA) represent one of the fragile patient groups that might be susceptible to the critical form of the coronavirus disease − 19 (COVID-19). On the other side, RA patients hav...

    Authors: Mahmood Y. Hachim, Ibrahim Y. Hachim, Kashif Bin Naeem, Haifa Hannawi, Issa Al Salmi and Suad Hannawi

    Citation: Translational Medicine Communications 2020 5:14

    Content type: Research

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  17. Infectious bronchitis (IB) is a highly contagious respiratory disease in chickens and produces economic loss within the poultry industry. This disease is caused by a single stranded RNA virus belonging to Cron...

    Authors: Eman A. Awadelkareem and Sumaia A. Ali

    Citation: Translational Medicine Communications 2020 5:13

    Content type: Research

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  18. Available studies are lacking in analysis of baseline demographics and hospital presentation of patients at risk of expiring due to coronavirus disease 2019 (COVID-19), particularly Black American patients. We...

    Authors: James Andrew McCracken, Mohamed Nakeshbandi, Jeffrey Arace, Wayne J. Riley and Roopali Sharma

    Citation: Translational Medicine Communications 2020 5:12

    Content type: Research

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  19. Surgical cryothermia and radiofrequency (RF) ablations for atrial fibrillation (AF) seem to result in similar sinus rhythm restoration, but the biochemical consequences of the two methods are unclear. We aimed...

    Authors: Gabriella Boano, Meriam Åström Aneq, Giannis Spyrou, Helena Enocsson, Emmanouil Charitakis and Farkas Vánky

    Citation: Translational Medicine Communications 2020 5:11

    Content type: Research

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  20. The bioelectric impedance analysis permits to estimate electrical parameters and body composition of subjects who are either apparently healthy or sick with different pathologies. The aim of this study is to i...

    Authors: Taira Teresa Batista Luna, Maraelys Morales González, Manuel Verdecia Jarque, Tamara Rubio González, Soraida Candida Acosta Brooks, Antonio Rafael Selva Castañeda, Justa Carmen Columbié Regüeiferos, Victoriano Gustavo Sierra González and Luis Enrique Bergues Cabrales

    Citation: Translational Medicine Communications 2020 5:10

    Content type: Research

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  21. Cystic fibrosis is a rare recessive monogenic disease caused by loss-of-function mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. Recently developed CFTR-modulators (i.e. drugs th...

    Authors: Peter van Mourik, Sabine Michel, Annelotte M. Vonk, Jeffrey M. Beekman and Cornelis K. van der Ent

    Citation: Translational Medicine Communications 2020 5:9

    Content type: Protocol

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  22. Myocardial recovery with Left ventricular assistant device (LVAD) therapy is dichotomous with some patients obtaining remission from end-stage heart failure whereas most require transplantation or remain on pu...

    Authors: Kajari Dhar, Asmini KC, Fang Qiu, Hesham Basma, Krupa K. Savalia, Jocelyn Jones, Alexandra M. Moulton, Matthew C. Zimmerman, John Um, Daniel Anderson, Marshall Hyden and Brian D. Lowes

    Citation: Translational Medicine Communications 2020 5:8

    Content type: Research

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  23. Translating pharmacogenetic research findings that have shown clinical efficacy into sustainable, routine clinical care at the institutional level requires strong evidence of improved patient outcomes bolstere...

    Authors: Kenneth D. Levy, R. Ryanne Wu, Daisuke Goto, Michelle A. Ramos, Victoria M. Pratt, J. Kevin Hicks, Ebony B. Madden, Gillian C. Bell, Kathryn V. Blake, Michelle Cohen, Benjamin Q. Duong, James P. Franciosi, Lori A. Orlando, Kunal Sanghavi and Geoffrey S. Ginsburg

    Citation: Translational Medicine Communications 2020 5:7

    Content type: Research

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  24. A considerable portion of the HIV pandemic is composed of people under antiretroviral therapy, many of whom get a late diagnosis. Patients starting antiretroviral therapy (ART) at a very advanced stage of HIV ...

    Authors: Dámaris P. Romero-Rodríguez, Carlos Ramírez, Iván Imaz-Rosshandler, Christopher E. Ormsby, Amy Peralta-Prado, Gustavo Olvera-García, Fernanda Cervantes, Daniela Würsch-Molina, Jessica Romero-Rodríguez, Wei Jiang, Gustavo Reyes-Terán and Enrique Espinosa

    Citation: Translational Medicine Communications 2020 5:6

    Content type: Research

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  25. Diffuse large B-cell lymphoma (DLBCL) is a heterogenous blood cancer, but can be broadly classified into two main subtypes, germinal center B-cell-like (GCB) and activated B-cell-like (ABC). GCB and ABC subtyp...

    Authors: Ewan Hunter, Ronald McCord, Aroul S. Ramadass, Jayne Green, Jurjen W. Westra, Kirsten Mundt and Alexandre Akoulitchev

    Citation: Translational Medicine Communications 2020 5:5

    Content type: Research

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  26. Intense exercise is a systemic stressor associated with the release of “danger” molecules – alarmins, by damaged or dying cells into systemic circulation to evoke a sterile inflammatory response. Compared with...

    Authors: Jorming Goh, Peter Hofmann, Ning Hong Aw, Poh Ling Tan, Gerhard Tschakert, Alexander Mueller, Siew Cheng Wong, Frankie Tan and Linda Seo Hwee Gan

    Citation: Translational Medicine Communications 2020 5:4

    Content type: Research

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  27. Osteoarthritis is the most common joint damage that leads to cartilage destruction, pain, and disability. The aim of this study is to investigate the effects of resistance exercises and Nano curcumin supplemen...

    Authors: Sadegh Cheragh-Birjandi, Meysam Moghbeli, Farideh Haghighi, Mohammad Reza Safdari, Maryam Baghernezhad, Arash Akhavan and Reza Ganji

    Citation: Translational Medicine Communications 2020 5:3

    Content type: Research

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  28. Cystic fibrosis (CF) lung disease is associated with chronic inflammation leading to progress in lung function. Adiponectin is a predominantly anti-inflammatory adipokine that may have a role in CF lung. This ...

    Authors: Atqah AbdulWahab, Mona Allangawi, Merlin Thomas, Ilham Bettahi, Siveen K. Sivaraman, Jayakumar Jerobin, Prem Chandra, Abdul-Badi Abou-Samra and Manjunath Ramanjaneya

    Citation: Translational Medicine Communications 2020 5:2

    Content type: Research

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  29. Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) are an immature cell type that inhibits the effector functions of T lymphocytes in chronic HIV infection. A well-known immunological feature of th...

    Authors: Eva M. Grützner, Ashley Neizert, Renate Stirner, Raffaele Conca, Immanuel Andrä, Lisa Wolff, Matthias Schiemann, Lesca M. Holdt, Christoph Klein, Johannes R. Bogner and Rika Draenert

    Citation: Translational Medicine Communications 2020 5:1

    Content type: Research

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  30. Colorectal cancer (CRC) can be considered as a result of multiple risks factors, and the significant role of infectious ones, especially viral diseases could not be underestimated. Despite endorsed attempts to...

    Authors: Shaian Tavakolian, Hossein Goudarzi, Behrang Kazeminezhad and Ebrahim Faghihloo

    Citation: Translational Medicine Communications 2019 4:20

    Content type: Research

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  31. Tooth hypersensitivity and pain are undesirable side effects of bleaching agents in humans. The aim of this study is to implement strategies to counter such side effects, and to demonstrate the efficacy and me...

    Authors: Diana Wang, Kawaljit Kaur, Avina Paranjpe, Eric Lee, Matthew Wasilewski, Danielle Sung, David Han, Eric C. Sung and Anahid Jewett

    Citation: Translational Medicine Communications 2019 4:19

    Content type: Research

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  32. A rift that has opened up between basic research (bench) and clinical research and patients (bed) who need their new treatments, diagnostics and prevention, and this rift is widening and getting deeper. The cr...

    Authors: Attila A. Seyhan

    Citation: Translational Medicine Communications 2019 4:18

    Content type: Review

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  33. We developed and clinically test a new method to manufacture mature dendritic cells for autologous cell therapy of solid and hematological malignancies.

    Authors: Leonardo Mirandola, Maurizio Chiriva-Internati, Robert Bresalier, Francesco M. Marincola, Jose A. Figueroa and Scott Dahlbeck

    Citation: Translational Medicine Communications 2019 4:17

    Content type: Research

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  34. This article presents examples of how to utilize the research output, to initiate academia-industry interaction, with the ultimate task of launching a new product: a smart heart valve prosthesis for pediatric ...

    Authors: Albert R. Liberski, Jonathan T. Butcher, Zbigniew Nawrat, Tal Golesworthy and Dena Ahmed Al Thani

    Citation: Translational Medicine Communications 2019 4:16

    Content type: Research

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  35. Mycoplasmas are ubiquitous pathogens found not only in humans but also in animals, plants, insects and soil. Though they usually grow better in an aerobic environment, mycoplasmas are also facultative anaerobi...

    Authors: Francesca Benedetti, Selvi Krishnan, Fiorenza Cocchi, Hervé Tettelin, Robert C. Gallo, Davide Zella and Sabrina Curreli

    Citation: Translational Medicine Communications 2019 4:15

    Content type: Research

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  36. Colorectal cancer (CRC) is the third most common cancer worldwide, and its incidence is expected to increase to over 2.2 million new cases in 2030. Stage II CRC is classified as localized disease, while stage ...

    Authors: Matilda Holm, Sakari Joenväärä, Mayank Saraswat, Tiialotta Tohmola, Ari Ristimäki, Risto Renkonen and Caj Haglund

    Citation: Translational Medicine Communications 2019 4:14

    Content type: Research

    Published on:

  37. Even as the eukaryotic stranded DNA is known to heterochromatinize at the nuclear envelope in response to mechanical strain, the precise mechanistic basis for alterations in chromatin gene transcription in dif...

    Authors: Hemant Sarin

    Citation: Translational Medicine Communications 2019 4:13

    Content type: Research

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  38. Prevalence of diabetes and comorbid brain disorders is increasing worldwide particularly in low- and middle-income countries. Diabetes and its complications impose substantial economic costs on the developing ...

    Authors: Ajit Kumar Thakur, Sakshi Tyagi and Nikhila Shekhar

    Citation: Translational Medicine Communications 2019 4:12

    Content type: Review

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  39. Interleukin-17A (IL-17A) is a potent pro-inflammatory cytokine that has been implicated in the pathogenesis of various autoimmune diseases. The production of IL-17A is commonly associated with subsets of CD4+ ...

    Authors: Pradeep K. Dagur, Elena Stansky, Ankit Saxena, Angélique Biancotto and John Philip McCoy Jr

    Citation: Translational Medicine Communications 2019 4:11

    Content type: Methodology

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  40. Understanding pediatric cancer biology is a huge challenge in continuous development that is currently being implemented into the clinical practice thanks to the new high throughput technologies integrated by ...

    Authors: Pablo Gargallo, Jaime Font de Mora, Pablo Berlanga, Inés Calabria, Margarita Llavador, Laia Pedrola, Joaquín Panadero, Sandra Dolz, Ángel Zúñiga, Juan Silvestre Oltra, Paloma Escobar, Yania Yáñez, María José Aparisi, Marina Martinez-Matilla, Vanessa Segura, Carlos Esquembre…

    Citation: Translational Medicine Communications 2019 4:10

    Content type: Research

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  41. Endometriosis impacts 6–10% of all reproductive- age women. Studies have shown the more effectively endometriosis is removed, the better the patient outcomes for pain reduction and fertility (2, 3). Hemosideri...

    Authors: Andrew G. Cabe, Arnold D. Estrada, Taylor Hoyt, Xiao Yang, Scott Jenney, Philip T. Valente, Bryan Cox, Jessica E. McLaughlin, Randal D. Robinson, Thomas E. Milner and Marc D. Feldman

    Citation: Translational Medicine Communications 2019 4:9

    Content type: Research

    Published on:

  42. Viral load (VL) monitoring in the clinical follow-up of HIV patients to detect treatment failure is not routinely offered in Cameroon. The study was designed to characterize virological response on antiretrovi...

    Authors: Juste Patient Mbébi Enoné, Calixte Ida Penda, Serge Bruno Ebong, Madeleine Mbangue, Samuel Honoré Mandengué and Carole Else Eboumbou Moukoko

    Citation: Translational Medicine Communications 2019 4:8

    Content type: Research

    Published on:

  43. Tuberculosis (TB) remains a debilitating, deadly disease that warrants innovative research tools to fully understand the pathogenesis and host immune responses, particularly at the site of infection and diseas...

    Authors: Carly Young, Petri Ahlers, Andriette M. Hiemstra, Andre G. Loxton, Andrea Gutschmidt, Stephanus T. Malherbe, Gerhard Walzl and Nelita Du Plessis

    Citation: Translational Medicine Communications 2019 4:7

    Content type: Research

    Published on:

  44. Intraductal Papillary Mucinous Neoplasia (IPMN) are potentially malignant cystic tumors of the pancreas. IPMN can progress from low to moderate to high grade dysplasia and further to IPMN associated carcinoma....

    Authors: Mayank Saraswat, Heini Nieminen, Sakari Joenvaara, Tiialotta Tohmola, Hanna Seppänen, Ari Ristimäki, Caj Haglund and Risto Renkonen

    Citation: Translational Medicine Communications 2019 4:6

    Content type: Research

    Published on:

  45. Apoptosis inhibition depends on the balance between expression of some regulatory genes including Bax and c-FLIP, despite breast cancer has long been associated with disturbances in apoptosis regulation. The obje...

    Authors: Esmaeil Mahmoudi, Mahdieh Abolfathi, Naiemeh Hassanzadeh, Yaser Eshaghi Milasi, Mina Dehghani-Samani, Mansoor Khaledi, Hossein Kerdarian, Mina Najafipour and Asghar Arshi

    Citation: Translational Medicine Communications 2019 4:5

    Content type: Research

    Published on:

  46. The CD39/CD73/adenosine suppression pathway correlates with disease progression in patients with chronic human immunodeficiency virus 1 (HIV-1) infection; however, the relationships between this pathway in B c...

    Authors: Wen-Xian Chang, Hui-Huang Huang, Lei Huang, Ji-Jing Shi, Yan-Mei Jiao, Chao Zhang, Lei Jin, Tao Yang, Ming Shi, Bo Tu, Zhe Xu, Tian-Jun Jiang, Fu-Sheng Wang and Ji-Yuan Zhang

    Citation: Translational Medicine Communications 2019 4:4

    Content type: Research

    Published on:

  47. Diabetes Mellitus (DM) is a chronic disease characterized by elevated levels of glucose in the blood. With time it becomes uncontrollable and invites other complex metabolic diseases. The propensity of the peo...

    Authors: Abhinav Kanwal and Liston Augustine Dsouza

    Citation: Translational Medicine Communications 2019 4:3

    Content type: Review

    Published on:

  48. Although durable clinical responses are achieved in a significant number of patients given Immune checkpoint inhibitors (ICI), like anti-CTLA-4 and anti-PD-1 inhibitors, some of the cancers have shown little o...

    Authors: Puneet Singh, Paul de Souza, Kieran F. Scott, Bruce M. Hall, Nirupama D. Verma, Therese M. Becker, James W. T. Toh, Mila Sajinovic and Kevin J. Spring

    Citation: Translational Medicine Communications 2019 4:2

    Content type: Review

    Published on:

  49. Leptin, a pleiotropic hormone is produced by adipose tissues and plays a critical role in various biological functions. Leptin mediates its function through interaction with specific receptors. The leptin-rece...

    Authors: Iman W. Achkar, Ajaz A. Bhat, Maria Zafar, Madiha Abbas, Omar S. Khan, Shilpa Kuttikrishnan, Kirti S. Prabhu and Shahab Uddin

    Citation: Translational Medicine Communications 2019 4:1

    Content type: Review

    Published on:

  50. Autoimmune diseases are syndromes characterized by an immune response against self-antigens. They are complex pathologies associated with a variety of genetic determinants, but these genes cannot fully explain...

    Authors: Leydy Katherin Duque Suárez, Gerardo Quintana López, Paola Ximena Coral Alvarado, Paul Alejandro Méndez Patarroyo, Helena Groot deRestrepo and Valeriano López-Segura

    Citation: Translational Medicine Communications 2018 3:11

    Content type: Research

    Published on:

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Translational Medicine Communications

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