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Table 2 Echocardiography data 2 and 28 days post-MI

From: Thymosin beta 4 treatment improves left ventricular function after myocardial infarction and is related to Up-regulation of chitinase 3-like-1 in mice

 

Control (n = 9)

TB4 i.p. (n = 8)

TB4 i.mc. (n = 9)

EF at day 2 post-MI (%)

42.5 ± 4.0

41.6 ± 2.6

39 ± 3.8

EF at day 28 post-MI (%)

38.2 ± 6.3

41.5 ± 3.9

41.2 ± 4.5

ESV at day 2 post-MI (μl)

43.3 ± 7.5

45.5 ± 5.2

48.7 ± 9.6

ESV at day 28 post-MI (μl)

58.5 ± 18

49 ± 7.0

51.7 ± 14.3

EDV at day 2 post-MI (μl)

75.2 ± 10.3

77.9 ± 8.4

79.3 ± 11.9

EDV at day 28 post-MI (μl)

93.3 ± 21.3

83.6 ± 7.5

86.9 ± 17.7

MI at day 2 post-MI by echo (%)

13.4 ± 5.7

17.7 ± 14.1

21 ± 8.9

MI at day 28 post-MI by echo (%)

21.7 ± 10

18 ± 10.5

20.5 ± 9.8

  1. All p = NS (mean ± SD)
  2. EF left ventricle ejection fraction, ESV left ventricle end-systolic volume, EDV left ventricle end-diastolic volume, MI myocardial infarction