Fig. 3

Morphological evaluation of infarcted hearts in CI or AC- induced CAD models. a Representative figures of late gadolinium enhanced scar area in both CAD models. The yellow arrows indicate that the scar area as confirmed by gadolinium staining. b Late gadolinium enhancement reveals that the scar area of AC-induced IHD models are more variable compared to the scar area found in CI-induced AMI models. c 2,3,5-Triphenyl-2H-tetrazolium Chloride (TTC) staining of infarcted hearts was performed to evaluate the scar area. The CI-induced AMI model also showed transmural MI. The yellow arrows indicate the scar area, identified by the absence of TTC staining. d Morphometric analysis also confirmed that the scar area of AC-induced IHD models is more variable compared to the scar areas found in the CI-induced AMI models. *p < 0.05