Fig. 2

CD39 and CD73 expression on B cell subsets in patients with chronic HIV-1 infection. a The gating strategy and phenotype of B cell subsets from one HIV-1+ patient. CD19⁺ B cells were firstly divided into immature CD10⁺ B cells and mature CD10⁻ B cells. Based on the differentiation markers CD21 and CD27, the mature CD10⁻ B cells were further divided into four subsets: CD21⁻CD27⁺ AM B cells, CD21⁺CD27⁺ RM B cells CD21⁺CD27⁻ naïve B cells, and CD21⁻CD27⁻ TLM B cells. b Pooled data showing the distribution of B cell subsets in each group. c Pooled data show the percentages of CD39⁺, CD73⁺, and CD39⁺CD73⁺ B cells in each subset. *p < 0.05, **p < 0.01, ***p < 0.001