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Fig. 2 | Translational Medicine Communications

Fig. 2

From: Skewed CD39/CD73/adenosine pathway in B cells is associated with innate immune hyperactivation in chronic HIV-1 infection

Fig. 2

CD39 and CD73 expression on B cell subsets in patients with chronic HIV-1 infection. a The gating strategy and phenotype of B cell subsets from one HIV-1+ patient. CD19+ B cells were firstly divided into immature CD10+ B cells and mature CD10 B cells. Based on the differentiation markers CD21 and CD27, the mature CD10 B cells were further divided into four subsets: CD21CD27+ AM B cells, CD21+CD27+ RM B cells CD21+CD27 naïve B cells, and CD21CD27 TLM B cells. b Pooled data showing the distribution of B cell subsets in each group. c Pooled data show the percentages of CD39+, CD73+, and CD39+CD73+ B cells in each subset. *p < 0.05, **p < 0.01, ***p < 0.001

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