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Fig. 5 | Translational Medicine Communications

Fig. 5

From: Skewed CD39/CD73/adenosine pathway in B cells is associated with innate immune hyperactivation in chronic HIV-1 infection

Fig. 5

The expression of adenosine receptors in monocytes and inhibition of the activation of monocytes by adenosine. a RT-PCR results are shown for relative expression of A1R, A2AR, and A2BR in monocytes isolated from HCs (n = 5) and TPs (n = 7). b MFI values of A2AR expressed on monocytes were higher in patients with AIDS. c Pooled data showing the expression levels of CD80, CD86, and HLA-DR on monocytes, and sCD14 released from monocytes in response to CADO under stimulation with LPS. d Pooled data showing the TNF-α expressing monocytes in response to various concentrations of CADO under stimulation with LPS. *p < 0.05, **p < 0.01, ***p < 0.001

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