Fig. 2
From: Differences and overlap in plasma protein expression during colorectal cancer progression
Pathway analysis for samples from patients with right-sided stage II and III CRC. a shows the top protein-protein interaction network generated by IPA. Proteins in red are proteins that were identified in our study and which displayed higher levels in patients with stage II CRC in the right colon when compared to patients with stage III CRC in the right colon. Proteins in white are proteins that, although not identified in our study, play roles in this network and interact with the proteins identified. b shows the protein interaction network generated by String analysis. The network shows known, direct protein-protein interactions from experiments and databases, without the addition of intermediate proteins not detected in this study, which IPA adds. Only proteins that passed the cutoff of having a Mann-Whitney U test p-value of less than 0.05 were used for pathway analysis