Fig. 4

Plasma levels of IL-8 and their correlation with the frequencies and suppressive capacity of PMN-MDSCs. a Plasma IL-8 levels were comparable in progressors (PR), controllers (CO), healthy controls (HC) and patients with lung cancer (BRO) (p > 0.098); however, the Kruskal-Wallis test for the comparisons of more than two groups reached significance (p = 0.037). b IL-8 levels correlated directly and significantly with frequencies (rho = 0.52, p = 0.0074) (b) and suppressive capacity (rho = 0.47, p = 0.019) (c) of PMN-MDSCs in all subjects. [PR: n = 10, CO: n = 5, HC: n = 5, BRO: n = 5, all subjects: n = 25]