Fig. 4From: AMP5A modulates Toll-like receptors 7 and 8 single-stranded RNA immune responses in PMA-differentiated THP-1 and PBMCRelative potency assay of AMP5A inhibition of CXCL10. Dose-dependent reduction in CL075-induced CXCL10 release from PMA-differentiated THP-1 by AMP5A. Data presented as regression analysis of percent inhibitions ± STD in 24 hour, CL075-induced CXCL10 release versus AMP5A serially diluted using saline diluent with concentrations listed as nominal in relation to full strength drug product. n = 9 for nominal 1 or full-strength product and n = 4 for all other dosesBack to article page