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Fig. 3 | Translational Medicine Communications

Fig. 3

From: Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine glioma

Fig. 3

Sagittal brain sections of FUS treated HSJD-DIPG-07 xenograft-bearing mice showing safety and BBB opening. Left: HE stainings indicating no tissue damage after FUS at 200 and 400 kPa. Middle: Human vimentin staining showing the diffuse growth pattern of HSJD-DIPG-07 xenograft. Right: Evans Blue extravasation after FUS showing an overlap with the human vimentin (tumor) staining at 400 kPa while at 200 kPa the tumor area is not covered

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